Nghiên cứu mối liên quan của một số yếu tố nguy cơ đối với tình trạng viêm quanh răng ở một nhóm người Việt Nam

NGHIEN m MOI UEN QUAN CUA MOT SO YEU TO NGUY C0

DOI vdi TINH TRANG VIEM QUANH RANG OMOT NHdM NGlrtTl VIET NAM

TOM TA T

Muc tieu: Nghien cdu nhim xac dinh moi Hen

quan ciia cac yeu to nguy ca nha sa cd mit cua mgt

so vi khuan dac hieu trong tui quanh rang, tinh trang

hut thuoc la, tuoi, gidi...vdi tinh trang pha huy vimg

quanh rang tren mot nhdm ngadi Viet Nam. Ddi

tupng va phuong phap: nghien cifu benh chdng tren

113 ddi taong tuoi ta 20 den 65 gom 75 benh nhan

VQR va 38 ngadi cd vung quanh ring khoe manh.

Cac doi tagng daac kham toan bd hai ham, ghi nhan

cac chi so lam sang, tinh trang hiit thuoc la va lay

miu mang bam dadi Igi. Cac miu mang bam daac

xet nghiem vi khuan gay benh bing phaong phap

PCR va nudi cay phan lap. Cac chi so' lam sang va

ket qua xet nghiem vi khuan daac phan tich bing

phan mem thong ke y hgc Epi Info 6.04. Ket qua: Cd

moi Hen he chat che giaa sa cd mat cua

A.actinomycetemcomitans T.forsythensis, F.

Nucleatum, P.Intermedia va tinh trang hut thuoc la vol

OR (do tin cay 95%) lan lagt la 7,50; 3,31; 2,37 va

2,17. Tinh trang hiit thuoc la cd moi Hen quari chit che

vdi tinh trang mat bam dinh quanh rang lam sang va

tinh trang tich tu mang bam rang. Cd moi lien quan

chat che gida do t tren 35 vai benh viem quanh nA/ang

a nhdm doi tagng nghien cifu vdi OR (do tin cay 95%)

la 4,28 va p<0,01. Ket luan: Cac yeu to nguy ca nha

sa cd mit cua mgt so vi khuan die hieu trong tui

quanh ring, tinh trang hut thuoc la, tuoi ...cd Hen quan

chit che vdi tinh trang tien triin cua benh viem quanh

ring. Nhdng yeu to nay cd thS daac coi la yeu to chi

diim cho mde do tram trgng cua benh VQR va daac

sd dung de tien lagng cho ket qua dieu tn benh VQR.

Tif khoa: tui quanh ring.

SUMMARY

Objectives: to determine the relation between risk

factors such as the present of some putative bacteria

In sub- gingival plaque, tobacco smoking, age, sex and

periodontitis status in one Vietnamese ^roup.

Methods: it was case-control study that carried out In

113 subjects with the age of 20 to 75 included 75

periodontitis patients and 38 healthy periodontal status.

Based on full mouth examination, clinical criteria were

recorded and sub-glngival plaque samples were

collected. PCR and culture method was used to

determine the present of the putative micro pathogens

in samples. The result was analyzed by medical

software. Results: There was the closed relation

between the present of A.actinomycetemcomitans,

T.forsythensis, F. nucleatum va P.intermedia and

smoKing with OR (Cl 95%) was 7.50; 3.31; 2.37 va

2.17, respectively. The age over 35 years old had

TRjNH OINH HAI, NGUY§N THj H6N G MINH

Bgnh vien RSng Hdm Mat Trung utmg Hi N^i

firmly relation with periodontitis (OR was 4.28 and p

<0.01). Conclusions: The risk factor as smoking, age

effect directly to micro flora In sub-gingival plaque that

do effect the Initiation and progression of periodontitis.

Those factors could be considered markers for the

serious of periodontitis and was using for prediction the

outcome of treatment.

Keywords: periodontitis.

DAT VAN OE

Viem quanh rang (VQR) la mdt benh trong nhUng

benh rang mieng thudng gap Viet NPTI va la nguyen

nhan hang dau gay mat rang a lua tudi iren 45. TU

lau, ngudi ta da biet day la mot benh da nguyen nhan,

trong d6 yeu td benh can chinh la vi khuan trong

mang bam dUdi Idi va dap Ung miln dich ciia cd the.

Bieu hien va tien tnen ciia benh bi anh hUdng ciia rat

nhieu yeu td nhu dap Ung miln dich ciia timg ca the,

yeu td xa hdi, thdi quen an udng va ve sinh rang

mieng, cac yeu td toan than, yeu td di truyen, cae yeu

td tai chd, thanh phan vi khuan trong mang bam rang

va cac yeu td nguy cd khae. Nhieu nghien eifu mo ta

cat ngang, phan tich da bien da dUdc tien hanh de tim

kiem mdi lien quan giUa yeu td nguy ed va mUc dp va

tinh trang nang ciia benh quanh rang. Cac tac gia da

dUa ra mpt sd yeu td nguy cd eua viem quanh rang

nhU: gidi, tudi, dieu kien kinh te, trinh dr van hoa,

benh toan than, hiit thude la... (1). Oa co nhieu tac gia

tren the gidi bao cao ve mdi lien quan cua cac ylu td

nguy cd nay vdi tinh trang benh VQR, tuy nhien d Viet

Nam nhung nghien cifu ve van de nay cdn rat han

che. Muc tieu cua nghien cifu nay la danh gia mdi lien

quan ciia cae yeu td nguy cd la su cd mat ciia mpt sd

vi khuan dac hieu trong tiii quanh rang tudi, gidi va

tdnh trang hiit thudc la vdi tinh trang viem quanh rang

d mpt nhom ngUdi Viet Nam

OOI TUONG vA PHLTONG PHA P NGHIEN CQU:

.1. Ooi tUdng nghien ciiru.

Nghien eifu dUdc tien hanh tren 113 benh nhan tai

Khoa Nha chu Benh Vien Rang Ham Mat Trung Udng

Ha Noi trong do tudi tU 20 den 65 trong thdi gian tU

thang 5 den thang 11 nam 2009.

2. Thiet ke nghien ciru.

Nghien eifu mo ta cat ngang.

3. Chon mau va thu thap so lieu.

3.1 Chon mau: 113 ddi tUdng dUdc chia lam 2

nhdm.

*Nh6m 1(nh6m VQR): gdm 75 benh nhan dUdc

chan doan la Viem quanh rang man tinh the vifa va

Y HOC THUC HANH (751) - SO 2/2011