Tình hình kháng kháng sinh của các loại vi khuẩn phân lập được qua dịch phế quản ở bệnh nhân viêm phổi bệnh viện tại khoa HSCC nhi - Bệnh viện Xanh Pôn

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da. Tap chi Y hpe thyc hanh 2000;8(385):45-47.

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Technique and Experience. Abstract of XII. International

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Disorders (Web page). 1998

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42.

TINH HINH KHANG KHANG SINH CUA CAC LOAI VI KHUAN PHAN LAP DUtfC

QUA D|CH PHE QUAN QT BENH NHAN VIEM PHOI BENH VIEN

TAI KHOA HSCC NHI - BENH VIEN XANH PO N

m:

NGUYIN THI HONG NHAN, NGUYEN TRUNG THANH,

TRANG BfCH VAN vd cs

TOMTAT :

Muc tieu: X^c djnh vi khuin gay viem phoi nSng

qua dich ciy NKQ d tre em dwoc dieu tn tai khoa

HSCC Nhi benh vien Xanh Pdn. Nhan x6t tinh hinh

kh&ng khding sinh d cac chung phan lap dwoc qua

cay dich NKQ. Doi tirgng va phwong phip nghien

ciru : Gom 61 benh nhan dwoc chin do^n viem phoi

nang , dieu tn tai khoa HSCC Nhi, benh vien Xanh

Pon. Phwong ph&p nghien ciru: Md ta tien ciru. Kit

qua : 61 benh nhi bi viem phoi, trong dd so benh nhi

dwdi 1 tuoi ehiem 72%, ty le tir vong ehiem 23%,

100% benh nhi dwoc ciy dich phi quan sau khi da

dieu trj tai benh vien tren 48 gio, so lin ciy lit 159

lan, so lan moc vi khuan la 31 lin (ty le 19,5%). Vi

khuan Gram (-) ehiem 51,5%,, G (+) ehiem 42,4%,,

nam ehiem 6,1 %o. 60%, c^c chiing Streptococcii da

khdng vdi Ceftriaxone, 50%, khang vdi Ceftazidime,

100%, Ccic chung S. Pneumoniae da khing vdi

Amikacin, 86%, khing vdi Ceftriaxone. Cic chung P.

aeruginosa co ty le khing khing sinh vi tir vong rat

cao. Hien chi cd 50% chung P. aegurinosa la con

nhay cam vdi nhom khing sinh Imipenem.

TCr khda : viem phoi, khing khang sinh, benh vien

Xanh Pdn

SUMMARY:

Objective: Determine the bacterial etiologies of

severe pneumonia among pediatric patients treated

at ICU pediatric,, St Paul hospital using andotracheai

fluid cultures, and their antimicrobial resistance

patterns. Subject: 61 patients with severe pneumonia,

72%, under 1 year old, mortality was 23%,. All patients

had endotracheal fluid cultured after 48h of

hospitalizatioh with 159 samples and 31 samples

growth (rate 19,5%o). Gram negative bacteria were

seen in 51,5%>, Gram positive in 42,4%,, fungi in 6,1%.

60%o of Streptococcii found were resistant to

Ceftriaxone, 50%, resist to Ceftazidime. S pneumonia

resist to amikacine and ceftriaxone was 100%o and

86%,. The P. aegurinosa had high resistant rate and

mortality, only 50% of P aegurinosa were sensitive to

Imipenem.

Keywords: severe pneumonia, St Paul hospital

DAT VA N D^ :

Nhiim khuan benh vien Iu6n IS vin d l thd'i sy

tren toSn thi gid'i, Viet Nam cung khong IS ngoai 1$.

Theo cac so lieu thong k§ d PhSp nSm 2005, nhiim

khuan benh vien ehiem ti le tCr 5 den 10%. Theo

thong ke sa bp cua khoa Chong nhiim khuan Benh

vien Xanh Pon trong nhu'ng nam gan day, ti le nhiim

khuan benh vien hSng nam khoang tir 17 - 20%. Cdn

theo thong ke tai Benh vien Nhi Trung yang, ti le

nhiim khuan benh vien ehiem khoang 14,8%.

NgSy nay, khSng sinh da vS dang bj vi khuin

khang lai vdi chieu hyo'ng tang cao ISm giam hi$u

qua dieu trj.

Vi vay ehiing toi thyc hien de tSi nSy vd'i 2 muc

tieu :

Xac djnh tan suit vi khuan gSy viem phoi

benh vien a tre em tai khoa HSCC Nhi, benh vien

Xanh Pdn.

NhSn x6t tinh hinh khSng khSng sinh a cSc

chiing phan lap dype qua cay djeh NKQ.

D 6 I TU'O'NG, PHU'QNG PHAP NGHIEN CLCU :

1. Ddi tirpTig nghien cu'u :

- Gom 61 benh nhi tir 1 thSng tuoi den dyd'i 15

tuoi bj viem phoi nang vS rit nSng sau nhSp vien tir

48 den 72 gid', dype dieu trj tai khoa HSCC Nhi benh

vien Xanh Pon.

- Tieu chuan chan doan viem phoi theo : T l chirc

y te the gid'i

Y HOC THUC HANH (729) - SO 8/2010