Tế bào gốc mở ra thế giới sinh học chưa từng được khám phá

THANH T P Mdl - GONG NGHE Mdl - SAN PHAM Mdl n^

TE BAO GOC Ma RA THE GIOI SIIVH

HOC CHUA TIJIVG OUOC KHAIVI PHA

Ldn ddu tiin cdc nhd khoa hgc ddphdt hiin ra mdt qud trinh sinh hgc thiit yiu duge

ggi Id qud trinh tdng hgp protein ed thi nghiin ciiu trong ti bdo gde trudng thdnh -

dieu md edc nhd khoa hgc dd ddnh mdt thai gian ddi ditim kiem.

CAC nhk khoa hpc thudc Trung tkm

NghiSn cuu Nhi khoa cfla Dai hpc

Tky Nam Texas (CRI) cung da

chung minh dupc sd Iupng chi'nh xkc

protein do ckc te bko gde tao mku san sinh

se quyit dinh chuc nang cfla chflng.

Nhiing kham phk nky, dupc cflng bd

tten tap chi khoa hpc hkng diu thi gidi

Nature, do ludng su san sinh piotein, rapt

qua Uinh gpi Ik biin ddi, va cho fliiy dupe

qua trinh tdng hpp protein khflng chi Ik nin

tang cdt ldi ddi vdi ckch thflc ckc te bko

gde dupc diiu chinh, ma cdn quyet dinh

din kha nang tai sinh cfla chflng.

"Chflng tfli da md ra mflt linh vuc sinh

hpc te bko moi mk trudc day chua cd ai

phkt hien Uiiy," Tien si Sean Morrison,

Giko su nhi khoa tai CRI, cho biit. "Chua

cd ai nghien cflu su tdng hop protein ttong

cac te bko gde xfl ma. Nhung phkt hiSn nky

khflng nhiing cung cap cho chflng ta nhung

kiin thuc moi ve su diiu chinh cfla ti bko

gde, mk con md ra tiem nang nghien cflu

nhiing khkc biSt ttong tdng hpp protein tfl

nhiiu Ioai tibao ttong cothe. Chung tfli tin

rang, dky Ik mflt the gidi chua duoc kham

phk cfla sinh hpc cho phep ckc ti bko khkc

nhau tdng hpp protein d cac tde dp khkc

nhau vk theo nhung ckch khkc nhau, va

nhung khkc biet nay vfl cung quan ttpng

ddi vdi su sdng cfla te bko."

Phdng thi nghiSm cfla TS. Adrian

Salic's tai ttudng Y Harvaid da Uen hanh

Ti§n sT Robert A.J. Signer, (trai) niik ngtii§n ciJu sau ti§n sT

v^ TiSn sT Sean Morrison, Giam doc Vien Ngiiien cOu tr^ em

la cac tac gia chinti cua nghien ciiu.

Anh: Trung tam YlSUT Soutttmslem

bien dfl'i hoa hgc thudc khkng sinh

puromycin theo each lam cho no cd thi

thiy vk dim dupc sd lupng protein duoc

tdng hpp bdi cac ti bko don le bSn ttong ca

the. Robert A.J.Signei - nhk nghien cflu

sau Uen si d phdng thi nghiSm cfla TS.

Morrison, ddng thdi Ik tkc gia thfl nhit cua

nghien cflu nky, dk nhkn thiy loai thudc

thfl nay cd the dieu chinh phfl hpp di co thi

do ludng su tdng hop protein cua ckc tebko

gde vk cac te bko khkc bSn trong he thdng

tao mau.

"Nhung gi mk chung tfli thay dupc that

dkng kinh ngae. Phkt hien nky cho Uiiy,

ttong mfli gid, mfli loai te bko mau khkc

nhau sin sinh la sd lupng piotein lat khkc

nhau, vk cu thi ckc ti bko gde tdng hpp

protein it hon nhiiu so vdi bat ky cac ti

bko tao man khkc. "Kit qua cho thiy ckc ti

bko gde tao mku ddi hoi tde dp tdng hpp

piotein thap ban so vdi ckc ti bao tao mku

28 KCM-3.2014