Sự ổn định thị lực và khúc xạ sau phẫu thuật Lasik và một số yếu tố liên quan

TAP CHl NGHliN CLPU Y HQC

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Summary

ROLE OF IVABRADINE IN COLLABORATION WITH STANDARD

TREATMENT FOR POST PRIMARY PERCUTANEOUS CORONARY

INTERVENTION (PPCI) PATIENTS WITH ACUTE MYOCARDIAL

INFARCTION (Ml)

Role of Ivabradine in-patients with stable coronary artery disease has been well established,

however it has not been proved in AMI patients after PPCI yet. This study was designed to

evaluate efficacy and adverse drug reactions of Ivabradine in collaboration with standard

treatment of post PPCI patients with AMI. The results showed that Ivabradine as an add-on

therapy to post PPCI patients with AMI standard treatment decreased heart rate, improved

symptoms such as angina & dyspnea after 1 month of treatment (p < 0,01), reduced major

cardiovascular events, rehospitalisation for heart failure after 12 weeks of treatment compared to

control group. Ivabradine was proved to be well-tolerated and safe in clinical treatment In

conclusion, Ivabraidine in collaboration with standard treatment improves the quality of life and the

prognosis in AMI patients after PPCI.

Key words: Ivabradine, myocardial infarction, primary percutaneous coronary intervention

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64 TCNCYH 78 (1) - 2012