Nghiên cứu sàng lọc và định danh kháng thể bất thường ở bệnh nhân truyền khối hồng cầu tại Bệnh viện đa khoa Trung ương Thái Nguyên

TAP CHi Y DU'O'C LAM SAN G 108 Tap 8-So 1/2013

Nghien ciiu sang loc va djnh danh khang thi bdt thuong 6*

benh nhan truygn kh6i h6ng chu tai Benh vien Da khoa

Trung uong Thai Nguyen

Irregular Antibodies Screening for the Patients at the

National General Hospital of Thai Nguyen

Nguyen Ticii Dung, Ngu\t>ii Kieu Giang

Tran Van Tuvcii

Truong Dai hoc Y Duoc Thai Nguyen

Benh vien Trung trang Qudn ddi 108

Qua sang loc khing the bat thudng cho 316 benh nhan duoc truyen khdi hdng cau tai Benh vien da

khoa trung uong Thai Nguyen, tU thang 5-10/2012, budc dau chung tdi rut ra ket luan sau:

•Tyle khang the bat thudng dbenh duoc truyen mau la 3.79%.

-Tyle khang the bat thudng cd lien quan den so lan truyen mau,

- Cle trudng hop duoc dmh danh khang the cd anti C, anti c, anti e va anti M

Tdkhda- khang the bat thudng

Summary

Through irregular antibodies screening for 316 patients at the National General Hospital of Thai

Nguyenat2012, we draw the following conclusions'

-Therateof irregular antibodies in patients receiving bloods is 3,79%.

- The rate of irregular antibodies related to number of blood transfusions.

- Cases identified antibodies with anti C, anti c, anti e and anti M,

Keywords: irregular antibodies

1 • Dat van cfe

Miu rat quan trpng va can thiet cho sU sdng,

nhd cd mi u m l nhieu ngUdi benh da duoc cUu

song, nhung truyen mau cung cd the gi y ra nhUng

tai bien nghiem trong neu cac nguyen ti c ve an

toin truyen mi u khdng duoc tdn trong. SU phat

hien ra nhdm mau he ABO, Rh v l cle he nhdm mi u

hong cau khic da giiip cho viec truyen mi u hieu

qui v l an toan hon. Tai cle nUdc tien tien an toan

truyen mi u 6a 6dgc thUc hien mot each triet de ho i

Phan bicn klioa lioc: PGS.TS LE VAN DON

hop ve nhom mi u he ABO, Rh, va mdt sd nhdm mi u

khac, sing Ipc khang the bat thudng (KT6T) da duoc

thuc hien [2], [3], [5], [6], [7]. Trong khi dd tai nude ta

viec thuc hien an toan truyen mi u ve mat mien djch

cdn rl't han ehe, chung ta mdi chi dinh nhdm mi u

he ABO, lam phi n Ung cheo d dieu kien nhiet do

phdng thi nghiem, do vay viec sinh khang the bat

thudng d nhUng benh nhan da truyen mi u nhieu

lan la khd tranh khdi [1], [3]. Viec tien hanh sang loc

khing the bat thudng cho benh nhi n 6dac truyen

miu , dac biet benh nhi n da truyen mi u nhieu lan II

rat can thiet de di m bi o an toan ve mat mien dich

cho benh nhan.