Nghiên cứu phát hiện kháng thể bất thường hệ hồng cầu ở bệnh nhân Thalassemia truyền máu nhiều lần tại Bệnh viện đa khoa Trung ương Thái Nguyên năm 2011

Y HQC Vlft NAM THANG 8 • s6 BAC BifT/2012

NGHIEN Cliu PHAT HllN KHANG THE BJiT THIflOrNG Hi H6NG C£U

or BlNH NHAN THALASSEMIA TRUYI N MA U NHliU LAN

TAI BINI I VII N BA KHOA TRUNG UUNG THAI NGUYI N NA M 2011

Nguyin Thi Tdng*, Trin Tiln Thjnh**,

Nguyin Kilu Giang* vi cs.

T6MT&T

De tdng bUdc ning cao sy" an toan v i hieu

qua trong cing tic ttuySn miu lim sing, dfc

biet la sU hoa hdp v i mft mien djch giOa ddn vj

mau truyen va ngUdI bfnh la rat cSn thiit.

Trong dieu tri, bfnh nhin thalassemia la nhdm

binh nhan co sd lan truyin mau nhieu. Vi vfy,

cliijng toi Hen hanh nghien cdu phit hlfn khang

the bat thudng (iCTBT) he hong cau trin bfnh

nhan thalassemia tai Bfnh vien da khoa trung

uHng Thii Nguyin nam 2011. Mpc tliu: Xac

fflnh ty if khing the bat thudng va mpt so yeu to

lien quan d benh nhan thalassemia ttuyin mau

nhieu ian. Doi tUdng nghien cdti: 112 bfnh

nhan thalassemia ttuyen mau tCr Ian 2. PhUdng

phip nghien cihi: md ta cat ngang, vdi each

chpn mau thuan Ben. Ket qua: Ty le KTBT d

benh thalassemia dPPc truyen mau la 30,35%,

Ty li khing the bat thudng cd liin quan den so

lan truyen mau.

Tir khoa: Thalassemia, khang the bat

thu'dng, truyen mau nhieu lan.

SUMMARY

STUDY FOUND ABNORMAL ANTIBODY

FOR THALASSEMIA PATIENTS TO MANY

BLOOD TRANSFUSION IN THE THAI

NGUYEN HOSPITAL IN 2011

To gradually Improve the safety and

effectiveness in the clinical blood transfusion,

especially In terms of immune harmony between

units of blood transfused and the patient is

essential. During treatment, patients with

thalassemia Is a group of patients with multiple

blood transfusions so we fill the study found

abnormal antibody (ICTBT) system in patients

with thalassemia erythrocytes in the Central

Hospital of Thai Nguyen in 2011. Objective:

Determine the rate of abnormal antibodies and

some related factors in patients with thalassemia

blood several times. Subjects: 112 patients with

thalassemia from a blood transfusion. Method:

descriptive cross-sectional, with a convenience

sample. Results: The rate in thalassemia KTBT

transfusion was 30.35%, Percentage of

antibodies related to abnormal number of blood

transfusions.

Keywords: thalassemia, abnormal

antibodies, blood transfusions several time.

I, OAT VAN OE

Mau rit quan ttpng vi cin thilt cho sy

sing, nhd cd mau ma nhieu ngudi bfnh da

dupe cdu sing, nhung ttuyin miu cOng ci the

gay ra nhihig tai biin nghiem ttpng niu cac

nguyin tic vl an toin truyen miu khong dupe

tdn ttpng. Su phat hifn ra nhdm mau hf ABO,

Rh vi cac he nhdm mau hdng ciu khac da giip

cho vifc truyin mau hiiu qua va an toan hem.

Tai cac nude tiin tiln an toan truyen mau da

Trudng Bai hpc Y-Dudc Thai Nguyen

"Benh vlfn da khoa Trung udng Thai Nguyen

Pdan Wen khoa hoc: PGS.TS. Bui Thj Mai An

365