Luận văn prenatal exposure to nonylphenol for taiwanese pregnant women

THAI NGUYEN UNIVERSITY

UNIVERSITY OF AGRICULTURE AND FORESTRY

KIEU MANH TUAN

PRENATAL EXPOSURE TO NONYLPHENOL FOR TAIWANESE

PREGNANT WOMEN

BACHELOR THESIS

Study Mode : Full-time

Major : Environmental Science and Management

Faculty : International Program Office

Batch : 2013 - 2017

Thai Nguyen, 15/07/2017

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Thai Nguyen University of Agriculture and Forestry

Degree program Bachelor of Environment Science and Management

Full name KIEU MANH TUAN

Student ID DTN1353070205

Thesis title Prenatal exposure to Nonylphenol for Taiwanese

pregnant women

Supervisor Prof. Chen, Mei-Lien (National Yang-Ming University,

Taiwan)

PhD. Nguyen Thanh Hai( Thai Nguyen University of

Agriculture and Forestry)

Abstract:

Nonylphenol (NP) is a degradation product of nonylphenol ethoxylates

(NPEOs). it is well-known endocrine disruptors, which may cause estrogenic

effects. Although the adverse effects of animals are well established, the

epidemiological studies on the adverse effects of NP exposure are inconsistent and

contradictory. The aim of this study include: First, to determine NP levels in

Taiwanese pregnant women. Second, to evaluate the potential risk associated with

exposure to NP for Taiwanese pregnant women. Third, to examine the association

between prenatal exposure to NP and health effects.

A total of 30 pregnant women was followed-up in this study. Maternal urines

are collected to determine the NP levels. A questionnaire was used to collect socio￾demographic data about the participants. Information about birth outcomes was

obtained from medical records.

In 30 sample of maternal urine that collected have 2 sample are not detectable.

The Mean SD of NP levels in maternal urine was 17.08 8.19 ng/ml, the range of

NP levels (min-max) are 9.35 to 42.72 ng/ml, and Geometric mean(GM) is 15.7

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ng/ml (in 28 sample detectable).

This study demonstrates the NP exposure profiles for pregnant women and

infants in Taiwan. We can found the significant associations between characteristics

of mother and infant. However, there are no significant associations between

pregnant women urine NP levels and birth outcomes in this study. In addition, from

this research we know that in the body of Taiwanese pregnant women had NP

levels, which indicated a potential risk for Taiwanese pregnant women and infants.

Keywords Nonylphenol, pregnant women, maternal urine, birth

outcomes

Number of pages 36

Date of submission 20/09/2017

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