Khảo sát mối liên quan giữa kiến thức và hành vi về vệ sinh phụ nữ với tình trạng viêm âm đạo tại bệnh viện Đa khoa Cần Thơ

tach ra khdi djch bao tuonq vypt gradient ndng dg nhy

la mpt chat nin vgn chuyen thieh hpp bdi Pgp. '"Tc￾MIBI cung dupe thay la higu qua hon TI-201 chloride

trong viec trong vige ddnh gid dap irng vdi hda trj d

bgnh nhan NSCLC va SCLC. Sy hap thu ^""Tc-MIBI bdi

eae t l bao ung thu lien quan din mpt vai ylu td (md

hpe: ddng mau va mgch mau; sinh hpc va hda sinh:

ehuyin hda t l bao va hogt dpng sdng; va sy bilu lp cua

gen MDR1) ma tac dpng din eae hoat dpng dupe ly cua

thude va kit qua eua hda trj. Bdi vgy, mipc do hap thy

^^"^Tc-MIBI ed the dupe gia djnh la kit qua cua nhiTng

can bing khae nhau giiTa nhiTng ylu td dd va nd cd the

dupe xem nhu la mpt cdng cy In vivo khdng xam lln de

danh gia dp nhgy cam vdi hda chat cua cac khdi ung

thu. Nd cung gpi y rang vige xae djnh mupc dp Pgp cua

bgnh nhan d thdi dilm chan doan hoac tai phat ed thi

ddng mpt vai trd quan trpng eho vige thilt k l phac dd

dilu trj sgu nay, ntiung nhilu nghien cuu khac nhau da

phat hign ra ring chi cd mupc dp bilu lp thip cua MDR1

d bgnh nhan ung thu phdi, bao gdm ca NSCLC va

SCLC. Sy hap thu ^^"'Tc-MIBI trong khdi u khdng nhat

thilt ehi ra ring mpt ung thu nhgy d m vdi thude la cd

lien quan vdi MDR1, bdi vi ed nhilu co chi khae nhau

cho sy khang da thude, nhu la sy khang da thude lien

quan din protein, sy tang Glutathion-S-tranferase, thay

ddi topoisomerase II, tang sy siTa ehCTa DNA, va sy

giam thap Cytoehrom p450 reductase. Bgnh nhan SCLC

vdi sy hap thp cao thi dap upng vdi hda trj tdt hon la

nhCTng bgnh nhan hap thy thap. Mpt bao cao cung chi ra

ring sy ving mgt cua hign tupng hap thu *'"Tc-MIBI

lien quan tdi vige that bgi vdi hda trj. NhCTng nghien curu

nay cung ehi ra ring miPC dp hap thu ^^'"Tc-MIBI d ung

thy phdi t l bao nhd ed lien quan tdi dap irng vdi hda trj.

Nhirng thdng tin thu dupe tif viec ghi hinh bing ^^""Te￾MIBI ed thi dupc SUP dyng trong dy bao qua trinh dien

biln eua ung thu vdi nhiTng bgnh nhan ma khdng dap

irng vdi hda trj thdng thudng, vi ed thi hudng din eho

vipc thilt k l mpt protocol dieu trj cd hieu qua nhat.

Theo nghien ciPU cua Masayuki Sasaki vd cpng sy

(1999) [14] eho thay dp nhgy cam vdi hda chat cd lien

quan mgt thilt vdi mupc do tap trung xg d pha sdm va ty

lg dao thai phdng xg

Chia-Hung Kao vi cpng sy (2000) [15] vdi nghien

CUPU dy bao sy dap ipng vdi paditaxel tren 30 b$nh nhin

ung thu phdi khdng te bao nhd blng^^^^c- MIBI SPECT

d pha sdm, so sanh ty sd giiTa sd dim eua khdi u va mo

lanh thay 85% ed dap irng tdt vdi hda chit va 16,7%

dap yng kem.

Can Ulman va cpng sy (2002) da tiln hanh nghien

cuu v l mdi lien quan giira miTc dp dap ung vdi hoa tri

ung thu phdi, tien lyong bgnh vdi ty sd tap tmng tgi u thay

giiTa chung cd mdi tuong quan tuyln tinh thugn chieu

tuong ddi ehgt che vdi hg sd tuong quan r = 0.73 [16].

Tdm Igi SPECT la mpt phuong phap ghi hinh y hpc

hat nhan cd gia trj trong chin doan va dilu trj bgnh ung

thu ndi chung, ung thu phdi ndi rieng. SPECT gdp phan

quan trpng trong viec chin doan khdi u d phdi, chan

doan giai doan ung thu phdi, la cdng cy giup theo doi

danh gia dap ipng cua cac phuong phap dieu trj mpt

each hiTu higu:'

TAI LIE U THAM KHA O

1. Bill Cdng Toan, Hoang Oinh Chan: Bgnh ung thir

phdi. Nha xuat ban Y hpc 2008, p 152, 153,154.

2. Advances in Nuclear Oncology - Diagnosis and

Therapy. Infonva Healtheam 2007. p61, 64,65, 66.

3. Gerrard A. Silvestri, Micheal K. Gloud, et al:

Noninvasive staging of Non-small cell lung cancer:

ACCP evidenced-based clinical practice guidelines.

Chest 2007; 132; 178S-201S.

4. Gupta et al. J Nuclear Med 1996; 37: 943

5. Patz et al. Radiology 1993; 188: 487

6. Chang CY et al. Incremental value of integrated

FDG-PET/CT in evaluating indeterminate solitary

pulmonary Nodule for maglinaney. Moi Imaging Biol

2009 Jun 20.

7. Vansteenkisteetal. J Clin Oncol 1998; 16:2142-9

8. Chin A Yi et al. 3T-MRI Usefulness for evaluating

primary lung cancer and small nodules in lobes not

containing primary tumors. AJR 2007; 189: 386-392.

9. Miw/a Morikawa et al. The effectiveness of '*F-FDG￾PET/CT combined with STIR MRI for diagnosing nodal

involvement in the thorax. Jnumed 2008.108.056408.

10. Mario Santini et al: The role of technetium-99m

hexakis-2-methoxyisobutyl isonitrile in the detection of

neoplastic lung lesions. Eur J Cardiothorac Surg

2009;35:325-331.

KHAO SAT MOI LIEN QUAN GIO'A KIEN THUTC VA HANH VI VE VE SINH PHU NUf

von TINH TRANG VIEM AM DAO TAI BENH VIEN DA KHOA CAN THO

TOM TAT

Nghidn cuv cat ngang md ta trdn 383 phg nir din

khim vi ra khi hw nhieu tgi phdng khim phg khoa bgnh

vign Da khoa Cin Tha cho thiy ty lg viem im dgo chung

37,1%, tmng dd nhidm khuin do Gardnrmlla vaginalis

12,3%o, Trichomonas 7,8%o, nim Candida 1,3%,. Cd S(/

Hen quan giira kien thire vi hinh vi eua phg nir trong

tinh trgng viem im dgo: phg nir ed kien thire khdng tot

vi vg sinh phg nii' ty lg viem im dgo eao han gip 2 lin

so v&i phg nCe ed kien thirc tot phg nw ed hinh vi ve vg

sinh phg nir khdng tdt ty lg viem im dgo cung cao hon

gap 2 tin; phg nir cd kiin thirc khdng tdt thi ed hinh vi

khdng tdt eao han gip 4 lin ngw&i cd hinh vl tdt Cic

yeu td ve nghi nghigp, tnnh dg hgc van, sH dgng ngudn

L A M OQ C TAM, NGUYINTH ! HU$

ntr&e ed lien quan den vidm am dgo

TCr khda: phg nu; viem am dgo

SUMMARY

A emss sectional study on 383 outpatients at Canttio

General Hospital shows that the pmvalence of vaginitis

is 37.1%, Trichomonas 7.8 %, Candida albicans 1.3 %.

Gardnemlla vaginalis 12.3%,. The women has not a good

knowledge about hyglent who has a double vaginitis as

compam with women has a good knowledge and

women's knowledge is not good, not good behavior 4

times higher than people with good behavibr Ttie

women has not a good skiH who has a double vaginitis

The factors of pmfession. education, and th^ source ot

102 Y HOC THUC HANH (751) - Sd 2/2011