Nhận xét tình trạng rối loạn Glucose máu ở bệnh nhân có hội chứng buồng trứng đa nang

DIEN DA N YHOC

Nghien cuu khoa hoc

NHAN XET TENH TRANG ROI LOAN GLUCOSE MAU

O BENH NHAN CO HQI CHCTNG BUONG TRIING DA NANG

!' '' Nguyen Khoa Dieu Van*; Do Xuan Manh**

TOM TAT

Muc tiSu.- nhgn xet tinh trgng roi logn glucose mdu va ddnh gid mdi tucmg quan giira glucose mdu

vdi mpt sd yen td khac a henh nhdn (BN) co hpi chimg budng trimg da nang (HCBTDN). Ddi tuong nghiSn

ciiu.' 49 BN cd HCBTDN tudi tie 18 den 38 den khdm tgi Benh vien Phu sdn Trung uong. Phuong phip

nghiSn cuu.' md td cdt ngang. Ddnh gid cdc rdi logn glucose mdu theo tieu chudn cita ADA 2003. Ket qua.'

dp tudi tnmg binh ciia BN la 25,27 ± 4.58 tudi, BMI trung binh a BN Id 20.3 ± 1,99 kg/nr. Trong 49 BN cd

HCBTDN. 28,6% BN bi roi logn glucose mdu (RLGM) (trong do 26.5%, BN rdi logn dung ngp GMvd I BN

hi ddi thdo duang chiem 2.1%). Khdng cd mdi tucmg quan giiea ndng dp GM luc ddi vdi dp tudi vd BMI

ciia BN (p > 0.05). Cd mdi tircmg quan thugn giiea ndng dp GMthdi diem 120 phiit (G2) trong nghiem phdp

dung ngp glucose mdu (NPDNGM) vdi dp tudi cua benh nhdn (r = 0.377; p < 0,05), nhimg khong co tucmg

quan giua G2 vai BMI (p > 0,05). KSt luan.- BN co HCBTDN co nguy ca mac cdc roi logn GMdu cdn ndng

binh thuang vd nguy ca mac RLGMcd xu hudng tdng ddn theo tudi.

LDATVANDE

Hdi chiing budng trung da nang (HCBTDN)

II rdi loan ndi tiSt thudng gap d phu nu', ty IS benh

cd the dat tdi 12% phu nu' trong dp tudi sinh de.

HCBTDN dugc dac trung bang tinh trang cudng

androgen (ram Idng, trung cl, tang tiet ba nhdn...),

vd sinh do mat phdng noan va/hoac budng triing da

nang. Benh dS lai nhieu hlu qui trudc mat, cung

nhu llu dii. Hlu qua trirdc mat la gay phiSn mudn

eho cac phu nu' trS bj HCBCDN II tinh trang rdi

loan kinh nguyet va vd sinh. Nhung dieu dang lo

ngai ho'n la hau qua lau dai ciia benh vdi nguy ca

mac dai thao dudng (DTD), biSn chiing tim mach

do liSn quan tdi tinh trang rdi loan dung nap glu￾cose mau (RLDNGM). Vi vay, viec phat hien kjp

thdi nhung RLGM bang djnh lupng glucose mau

va lam ngbiem phip dung nap GM (NPDNGM) khi

can se giiip ich eho viec phat hien sdin va sang Ipe

biSn ehung DTD d BN cd HCBTDN [2] [6]. Tren

thS gidi da cd nhieu nghien ciiu dinh gia rdi loan

GM d BN cd HCBTDN, nhung cho tdi nay tai Viet

Nam hien ed rat it nghien cuu vS van de nly. Vi

vay, ehiing tdi tiSn hinh de tii vdi 2 mue tiSu:

/. Nhgn xet tinh trgng roi glucose mdu a benh nhdn

CO hpi chimg buong trimg da nang.

2. Ddnh gid moi tieong quan giiea glucose mdu vai

mpt sd yeu td khac a benh nhdn co hpi chimg budng

trimg da nang.

II. DOI TirONG VA PHirONG PHAP

NGHIEN ctr u

1. Doi tugng nghien cuu

49 BN cd HCBTDN tudi tu 18 den 38 dSn

kham tai Benh vien Phu san Trung uong trong thdi

* Khoa Npi tiet - Ddi thdo dudng, Benh vien Bgch Mai

** Dgi hgc YHd Npi

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