Hội chứng chuyển hóa ở bệnh nhân tăng huyết áp có tuổi

cung ma cdn d ngay Idng vdi tnihg, do do sU di chuyen

tinh triing tir budng tuf cung qua vdi trtrng den gap noan

cung kem thuan Ipi. Cho dii ty le cd thai chUa cao

nhufng viec chi djnh I.U.I cho nhufng trUdng hdp chat

nhay cd tii cung kem, dudi 2222 diem la rat can thiet

de tang kha nang cd thai trong dieu trj V'sinh. Nghien

cufU ciia chiing tdi cung tuong tU vdi ket qua cd thai ciia

Nguyin Thj Xiem trong I.U.I la 18%.

KET LUAN

Tir cac ket qua nghien ciiu thu dupe, ehiing tdi rut

ra mdt sd ket luan sau:

- Lieu 50 mg/ngay gay duoc phdng noan la 70,2%

sd vdng dieu trj va cd thai dat 22,4% sd benh nhan

dieu trj. Day la lieu gay dupc phdng noan, va cd thai

cao nha't.

- Lieu 100 mg/ngay gay dupc phdng noan la

60,8% sd vdng dieu trj va cd thai la 17,8% sd benh

nhan dieu tri.

- Lieu 25 mg/ngay cung gay dupc phdng noan va

cd thai.

- Ty le gay dupc phdng noan cua CC la 68%, va ty

le cd thai trong vdng kinh cd phdng noan dat 16,2%.

- Tac dung phu do CC gay ra lam giam chat nhay

cd tli cung, ngan can su di chuyen ctia tinh triing cho

viec thu tinh vdi trtifng.

KIEN NGHj

Nen chi djnh rdng rai clomifen citrat cho tat ca phii

niif vd sinhnguyen nhan do khdng phdng noan va kho

phdng noan trong giai doan hien nay, trUdc khi diing

cac thudc kich thich phdng noan khac thay the.

TAI LIEU THAiVI KHAO

1. Nguyin Khac Lieu. Kich thich phdng noan. Chan

doan va dieu trj v"sinh, 10/1999; 109.

2. Dickey pi.P, Taylor S.N. Incidence of spontaneous

abortion in elomiphen pregnancies, hum reprod; 1996,

11,2623.

3. Garcia J, Jone G.S. The use of clomifen-citrate;

Fertil. Steril; 1977, 28, 7, 707.

4. Hugues J-N. Induction d'ovulation par le citrate de

clomifen, Gyne'cologic-Obste'trique; NO 28 fevrier 1998,

5-10.

5. Lobo P.S, et al. Induction of ovulation by

clomiphene citrate; vol 5 chap 68, Reproductive

Endocrinology Infertility Genetics 1997. 346.

6. Wu CH, Winkel CA. The effect of therapy

initiation day on clomiphene citrate therapy, Fertil- Steril,

1989, 52-564.

HOI CHQMG CHUYEN HOA a BENH NHAN TANG HUYET AP Cd TUOI

T6M TAT

Hdi chimg chuvin hda (HCCH) ngiy cing dugc si/

quan tam ciia nhieu chuydn gia y te vi nd lam tang ti lg

b$nh dai thio dadng, bdnh mach vinh, dgt quy, ti Id tir

vong chung cung nhu ginh n$ng vd y te.

Chiing tdi tien hinh nghien cim niy nhim mtje dich

xic dinh tan xuat (HCCH) a ngudri ting huyet ip cd tuoi

dong thdi khao sit sa thay doi sa thay doi ciia hgi chimg

niy trong qui trinh tich tuoi.

Nghien cim duv^ tien hinh tmng vdng 12 thing td

thing 10/2005 den thing 9/2006 bao gom tat ca la 532

bgnh nhan tang huyet ip ed tuoi ehiing tdi rut ra dirge

ket luin nhu sau:

- Ty lg bgnh nhin ting huyet ip cd (HCCH) rat cao

li 58,6%) theo tieu chuan ATP III ed hlgu chinh vdng eo

a ngadi Chiu A. Ti lg niy thay doi theo gidi tinh nir

nhieu han nam.

- Cd sa gia tang theo tuoi ve ti lg (HCCH) qui trinh

tich tuoi.

- Thinh phan thuvng gap nhat xuat hi$n tmng

(HCCH ) d bgnh nhan THA ed tuoi lan Itrgt li tang

triglycerid (85%), giam HDLc, ting vdng eo vi sau cung

li ting dadng huyet

Td khda: Hgi chung chuyen hda, tang huyet ip

SUMIVIARY

Medical specialists take interest in metabolic

syndmme more and more because it makes the rate of

diabetes, comnary disease, stroke, and general death

increase as well as the burden of medical

We do this research aim at specifying the level of

PHAN HA I PHJON G

metabolic syndrome on eldedy hypertensive patients

and simultaneously studying the changing of this during

the stored age process.

The reseamh is carried out within 12 months, from

October 2005 to September 2008, including 532 elderly

hypertensive patients. After studying, we have the

following msults:

- The rate of hypertensive patients who have high

metabolic syndrome is 58,6% according to the ATP III

criterion with the adjustment of waist size of the Asian.

The changes of this rate depend on sex, female changes

more than male.

- There is an increasing on age for the rate of

metabolic syndrome in the stored age process.

The components which often appear in metabolic

syndmme on eldedy hypertensive patients are triglycerid

and waist size increasing, HDLc decreasing, and finally

that is the Increasing ofglycaemia

Keywords.medical, hypertensive

OAT VAN Dt

Hpi chifng chuyen hda dup'c G.M Reaven mo ta vd

dat ten la hpi chirng X duoc dgc trung bdi Si,!' hien dien

ddng thdi cac tri^u chifng nhu beo phi (d$c bi^t beo phi

trunp tam), rdi logn lipid mau, tang dudng huyit va tSng

huyet ap [61.

Tan suat HCCH tang theo tuoi anh hudng khoang

40% ngu'di tren 60 tudi [10]. Sy- hi$n dien cua hpi chieng

chuyen hda quan trpng ddi vdi nguy co benh tim mach,

dai thao dudng tip 2 va cd nhu-ng bing chirng mdi dSy

cho thay sy hien dien HCCH ket hop vdi sg- gia tang nguy

60 Y HOC THirc HANH (751) - S6 2/2011