Hiệu quả và tính an toàn của Vigadexa trong điều trị viêm kết mạc

TAP CHl NGHliN CO'U Y HQC

Summary

PRELIMINARY RESULTS OF MINIRADICAL TRANSCANAL

MASTOIDECJOMY

The study was to evaluate the preliminary results of miniradieal transcanal mastoidectomy.

The results showed that 17 females / 8 males, aged from 16 to 67 years olds. 22 pafients (pts)

were done reeonstruefive tympanal cavity. By the 10"^ day post -operation 22/25 pts were without

otorrhea, 2 months post operafion the miniradieal mastoidectomies were stable,with the width of

external auditory canal twice than a nomal one with ear-hole enough to drain. In conclusion, this is

an minisurgery with perfect cavity of mastoidectomy, which has faster recover time and make

good conditions for hearing reconstruction.

Keywords: cholesteatoma, retraction of tympanic membrane, transcanal antrotomy,

miniradieal mastoidectomy

HIEU QUA VA TiNH AN TOA N

CUA VIGADEX A TRON G DI^ U TR! VIEM KET MAC

Nguyin DiPC Anh

Trwdng Dai hpc Y Ha Npi

Nghien cuv nham danh gid hipu qua deu trj va tinh an todn cua thude tra mat Vigadexa® (moxifloxacin

0.5% vd dexamethasone 0,1%) d benh nhdn vidm kit mpc cap. Kit qua cho thiy trwdc deu tri 118 mat

(79,2%) vidm mdc dd nhp vd tmng binh, 31 mat (20,8%) viem npng, trong dd 14 mat (9,4%) cd gia mac vd 8

mat (5,4%) vidm gidc mpc. Sau diu th, tl lp khdi bpnh hoan toan Id 67,8 % sau 8 ngay va 87,2% sau 12

ngdy. Khdng xuit hipn biin Chung do dung thudc. Kit lupn: Vigadexa® td ra cd hipu qua cao tmng deu tri

vidm kit mpc cip. Thudc khdng gdy kich dng hope tdc dung phu tai mat. Dpng thude phdi hgp thupn tien

han cho sw dpng, gidm chi phi va tang hipu qua diu trj.

Td khoa: Vigadexa, viem kit mac

I. DAT VAN Dt

ViOm kit mac la mdt bOnh mit thudng gdp

nhat Oilu trj viOm kit mac thudng bing mOt

thudc tra mit khang sinh phd rdng phdi hgp

vdi mot thude chdng viOm. ViOc su dung cung

IQc 2 thudc tra mit lam tang chi phi dilu trj vd

Id bat tlOn ddi vdi nhilu bOnh nhan khiln eho

thude dung khong du lilu va giam hiOu qua

dilu trj. Gin day, mot thude tra mit mdi la

Vigadexa® eua Alcon duge dua ra thj trudng,

trong dd kit hgp ca 2 ylu td khdng sinh

(moxifloxacin 5%) vd chdng viOm

(dexamethasone 0,1%). O ViOt Nam, chua ed

nghiOn c&u ddnh gid hiOu qui cua Vigadexa®

ddi vdi viOm kit mge. NghiOn c&u ndy nhim 2

mge fiOu: (1) ddnh gid hiOu qua diOt khuln vd

chdng viOm eua Vigadexa® ddi vdi bOnh viOm

kit mac dp ; vd (2) ddnh gid tinh an todn cua

thude ddi vdi ede bOnh nhdn dugc dilu trj.

II. D6 | TU'QNG VA PHU'ONG PHAP

Tieu chuln lua chgn: ede benh nhdn

viOm kit mge clp, tudi t& 18 trd lOn, kham tgi

bOnh viOn mit trung uang trong nam 2010.

TCNCYH 78(1) 2012- 53