Tìm hiểu mối liên quan giữa các yếu tố nguy cơ cao với tỷ lệ đái tháo đường thai kỳ

BTl^ibai

B Tu tuvcn duui

• Coihai

Q Tac dung ptv

Q Roi ban chuvcn hoa Ipdc

• R6i ban latn than

• Botn

n Tir \'one

B Ding tir dau

DTu Hong Kong It

Bieu do 2: Nguyen nhan sirdv"0 <'&<. dp bachai

Ve mufc dp tuan thu eua cac benh nhan, chung tdi

tha'y 59 benh nhan (72,84%) cd mufc dp tuan thu tdt,

22 benh nhan (27,6%) cd mufc dp tuan thu trung binh

hoac khdng tuan thij dieu trj. Cac trudng hpp that bai

dieu trj cung thudng gap d cae benh nhan nay. Ket

qua nay cho tha'y mire dp tuan thu kem la mpt trong

nhirng nguyen nhan ehu yeu chuyen ddi phac dd d

benh nhan dUdc dieu tri bang phac dd bac mpt.

~ CD4 tmdc khi tha> phac dc

CD4saukhjlhayphk()6

Bieu do 3: So sanh sd liTdng te bao CD4 tnrde

va sau khi thay doi phac do

Trong nghien cufu nay chiing tdi tha'y cd su thay

ddi dang ke sd lupng te bao lympho TCD4* sau 6

thang ke tir khi thay ddi phac dd. Hau het cac trUdng

hpp cd sd lupng TCD4* cao hon trUdc khi thay ddi

phac dd (Bieu dd 3). Odng thdi trong sd 25 trudng

hop dupc xet nghiem tai lupng virus HIV sau khi

chuyen sang phac do bac hai cd tdi 21 trudng hdp

(84%) cd tai luong virus dudi ngudng phat hien, 4

trudng hdp (16%) cd tai lUdng tren ngudng phat hien,

tuy nhien tai lUdng virus cija cac trUdng hdp nay deu

khdng qua 100 copies/mL. Cac ket qua nay so bd cho

thay hieu qua dieu trj cua phac dd bac hai.

KET LUAN

Tir nghien cufu nay chiing tdi mt ra mpt sd ket luan

sau. Ty le benh nhan sur dung phac dd bac hai tai OPC

Viet Tiep, Hai Phdng ia 7,92%, ty le nam/nOf l i 2,69.

Cac nguyen nhan chu yeu cua gay chuyen sang phac

dd bac hai la tha't bai dieu tri, tac dung phu cija cac

thudc ARV, cd thai va suf dung tU dau d ndi khac

chuyen ve. Cac yeu to thuan lOi din den tinh trang that

bai dieu tri la khdi ddng dieu trj khi cd sd luong te bao

lympho TCD4* tha'p va mirc dp tuan thu tmng binh

hoac khdng tuan thu. Cac benh nhan dieu tri bang

phac dd bac hai cd ket qua dieu trj tdt khi cd sd luOng

te bao lympho TCD4*tang va tai luong virus giam dudi

ngudng phat hien. Cac xet nghiem dem tai lupng virus

HIV, dem sd lupng te bao lympho TCD4* can dupc ap

dung mpt each thudng quy nham phat hien sdm cac

trudng hpp tha't bai dieu tri de cd the chuyen ddi phac

dd phu hop. Can day manh hon ntifa cdng tac giao due

dieu trj nham nang cao mufc dp tuan thu cua benh

nhan, han che xua't hidn khang thudc.

T A I LIEU THAM KHA O

1. Bd Y te. Bao cao tinh hinh nhilm HIV/AIDS ndm

2009.

2. Bd Y te. Hudng dan chan doan va dieu tri

HIV/AIDS nam 2005. Nha xua't ban Y hpe.

3. Bd Y te. Hudng din chan doan va dieu tri

HIV/AIDS nam 2009. Nha xua't ban Y hpe.

4. Girard P.M, Katlama C, Pialoux G (2007).

Traitements antiretroviraux. Dans: VIH; edition 2007; PP

335- 369. Doin editeurs, Rueil-Mailmaison Cedex.

5. Yeni P (2008). Traitement antiretroviral. Dans:

Prise en charge medicale des personnes infectees par le

VIH: Reeommandation du groupe d'experts; Rapport

2008. PP 32-60. Medecine-Seienees Flammarion

editeur, Paris.

6. WHO. Antiretroviraux therapie for HIV infection in

adults and aldolescent. Revision 2010.

7.http://data.unaids.org/pub/EPISIides/2007/2007_ep

iupdate_fr.pdf.

8.http://data.unaids.org/pub/Report/2009/JC1700_Ep

i_Update_2009_en. pdf.

TIM HIEU MO I UE N QUAN GIOA CAC YEU Td NGUY CO CAO

VAl TY LE DAI THAO DUONG THAI KY

TOM TAT

Muc tiiu; Tim hiiu mdi lidn quan giira fj? le DTDTK

vdi cac yeu td nguy ca cao. Ddi tugng vd phuang

phdp nghiin ciiv: nghien cifu tien cifu md ti, 160 thai

phu cd yiu td nguy cd cao daac quan ly tai khoa kham

benh Benh vien Phu san Trung Uang ti/ 01/01/2010

den 30/06/2010 chaa daac chan doan DTD, khdng

NGUYI N TH! KIM LieN, OAN G TH I MINH NGUY$T

Tru&ng Dai hgc Y Hd N^i

mic cdc b$nh liin quan chuydn hda glucose, khdng

dung cac thudc inh hudng chuydn hda glucose. Cic

thai phu dt/gc lam nghi&m phap dung nap glucose miu

ngay lan kham thai dau tien, neu im tinh lim lai

nghiem phap dung nap glucose vao tuan thd 24 -28

thai ky. Kit qua; Sakhac biet cd y nghia thdng kd giOa

46 Y HOC THirC HANH (751) - S6 2/2011