Thực trạng những khó khăn khi triển khai mô hình phòng y tế theo thông tư liên tịch số 11/2005/TTLT-BYT-BNV tại các huyện trong toàn quốc, năm 2008

trpng lifdng cao hon cd y nghTa so vdi Id udng nirdc

cat. Nifdc sac va vien nang Thdng ta yeu phuang da

cai thien kha nang tieu hda cua chudt bj gay md hinh

HCRKT, gdp phan lam tang trpng lupng co the chudt.

TTYP da ed tac dung lam can bang ham lUdng

nude trong phan d ea hai the phan tao va Idng vdri

hieu qua rd ret sau khi dimg thudc. GiOra hai dang bao

che cua thudc cd tac dung nhU nhau vi sU khae biet

khdng cd ^ nghTa. TTYP cd vai trd dieu chinh can

bang lai ham lUdng serotonin trong huyet tUdng, b ea

hai the phan tao va Idng deu cd hieu qua rd ret sau

khi diing thudc, dua ehl sd ve gidi han binh thudng.

SU can bang ve ham lupng nude trong phan va ham

lUdng serotonin trong mau eung anh hudng tdi tinh

chat va hinh dgng phan thdng qua viec giam trieu

chimg b ea hai the phan tao va Idng. Bai thudc TTYP

b hai dang bao che da cd hieu qua dieu tri rdi loan

tinh chat phan rd ret vdi mUe dd tUdng dUdng tren

thUe nghiem.

Dieu chinh rdi loan ve hinh vi

Chudt b hai Id sau udng thudc TTYP (nude sac va

vien nang) cd thdi gian suf dung kham pha viing trung

tam tang len nhieu hdn so vdi chudt d trang thai stress,

"va eung nhieu hdn chudt b Id udng nude cat. Tuy rang

chudt b Id udng nude eat fed eai thien hdn chudt d

trang thai stress. Dieu nay chUng td thudc TTYP da eai

thidn ve mat yeu td tinh than, nhanh ehdng giup chudt

binh tam trd lai va thich nghi vdi mdi trudng mdi xung

quanh. Chudt sau khi dUdc dieu trj thudc nhu tren da

giam dang ke thdi gian sCf dung d khoang 2, va tang

thdi gian sCf dung b khoang 3, ddng thdi sd ldn vao ra

cac khoang cung nhilu hdn so vdi chudt sau stress.

Vdi bai tess nay ta thay thudc TTYP cd hieu qua lam

tang eudng hoat ddng eua chudt, giiip chudt nhanh

nhen hoat bat, dac biet la tang sU tiep xiic vdi ddng

loai. TU hai bai t->ss tren cho thay, thudc TTYP d hai

dang bao che cd tac dung can bang lai trang thai sau

tress, cai thien mpi hanh vi, giiip chudt trd ve ban nang

ban dau vdn ed cua chiina. • —.,•••

K^LUAN • • ' "" ' - ^^ -

Vien nang Thdng ta yeu phUdng (bao che theo

phUdng phap hien dai) va thudc sic cua bai Thdng ta

yeu phUdng (bao che theo phuong phap cd tmyen) ed

tac dung dieu trj HCRKT tren thuc nghiem tUdng

dUdng nhau:

MUc tang trpng lUdng cd the sau khi dieu tri bang

vien nang va nude sic TTYP khdng ed sU khac biet,

ca hai Id dieu tri thudc cao hdn ed y nghTa so vdi Id

udng nudc cat. Ty le phan tao va Idng eua 2 Id udng

Thdng ta yeu phUdng da giam ed y nghTa so vdi thdi

diem trudc dieu trj. Hai Id chudt dieu trj Thdng ta yeu

phUdng cd ham lUdng nudc trong phan giam (ddi vdi

tmdng hdp phan Idng) va t§ng (ddi vdi tnrdng hdp

phan tao) gan vdi binh thudng. Cae dau hieu benh ly

da suy giam. Ham lUdng serotonin trong huyet tUdng

ciia ea hai Id dieu trj bang Thdng ta yeu phUdng trd

ve vdi mUc binh thudng. Chudt d 2 Id dieu trj bang

Thd'pg ta yeu phUdng cd sUthay ddi hanh vi dang ke

so vdi id udng nUdc cat, cac dau hieu stress giam dan

va trd ve trang thai binh thudng.

TAI LIEU THAM KHAO :

1. Ha van Nggc va cpng sy (1996), NhOng die diim

lim sing vi cgn lim sing tren 215 tnrdng hgp HCRKT,

Tgp san Ngi khoa Vigt Nam. tr. 19-24.

2. Nguyen Thj Tuylt Nga (2007), Nghiin cdu tic

dung cua bii thuoc Td than hoin trong diiu trj hdi

Chung mgt kich thich the Idng, Luln van Tiln sT Y hpc.

Trudng Dgi hpc Y Ha Npi.

3. Nguyen Thj Nhuan (1999), Nghiin cuv tic dung

cOa bii thuoc Binh vj tan trong dieu tn r6i logn chirc

ning dgi tring, Luln van Bac si CKII, DH Y Ha Ndi.

4. Bili Thj Phuang Thao (2005), Dinh gii tic dgng

diiu tri rdi logn ca ning dgi tring bing vi§n nang Hi

Mg. Luan van thgc sT Y hoc, DH Y Ha Ndi.

5. Lgi Ngpc Thi (1996), Gdp phin nghiin cuv vi tin

suit vi djch te hgc ciia HCRKT, Luan van Thgc sT y hpc,

Hpevi^n Quan y.

6. Bradesi S, Schwetz I, Ennes HS, Lamy CM,

Ohning G, Fanselow M, Pothoulakis C, McRoberts JA,

Mayer EA. (2005), Repeated exposure to water

avoidance stress in rats: a new model for sustained

visceral hyperalgesia. Am J Physiol Gastrointest Liver

Physiol. 289: 42-53.

7. Peng L.H, Wang W. F, Yang Y.S, Gang Sun,

(2005), Change of substance P containing neural

pathway in rat model of initable bowel syndrome. World

Chin J Digestol 2005 January 15;13(2):214-218

8. Shuxiu Luo, Junkang Liu, Dewei Ai, Hailong Wei

(2006), Study on Relative Neurotransmitters of IBS

Animal, Biowave Science & Applied Oncology, pp 19-20.

9. Yu Ying-cong and Dai Ning (2007), Contmversies

and limitations in irritable bowel syndrome studies,

Chinese Medical Journal 2007; 120(23):2143-2145.

V-- 0 r -)• .„ • - •:• '?! ; :j<.

THUC TRANG NHQN G KHd KHAN KHI TRIEN KHAI NlO HJNH PHONG Y TE THEO THdNG TlT

LIEN TICH sd 11/2005/nLT - R H - RNV TAI CAC HUYEN TRONG TOAN QUdC, NA M 2008

DAT VA N Dt

Thye hi$n cai each hanh chinh, tang cudng edng tac

quan ly nha nude d cac clp Chinh phu da ban hanh

Nghj djnh sd 171/2004/NO-CP ngay 29 thang 9 nam

KHUONG VA N DUY, NGUYI N VA N Y^ N

NGUYI N VA N HAU , V^ cgng si/

2004 v l qui djnh td chirc cdc ca quan chuyen mdn thudc

UBND tinh, thanh phd tryc thudc Trung uang va Nghj

djnh sd 172/2004/ND-CP ngay 29 thang 9 nam 2004 v l

qui djnh td chirc cae ca quan chuydn mdn thudc UBND

Y HOC THl/C HANH (741) - S6 11/2010 21