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about the book…

Edited by ROGER S KIRBY, The Prostate Centre, London, UK; CULLEY C CARSON III, University of North Carolina

School of Medicine, Chapel Hill, NC, USA; MICHAEL G KIRBY, The Prostate Centre, London, UK; and ALAN WHITE,

Leeds Metropolitan University, Leeds, UK

The Third Edition of Men’s Health provides an authoritative reference source for urologists, andrologists,

general practitioners, and all professionals who diagnose and treat male patients with a variety of male health

problems, such as prostate cancer, male osteoporosis, and testicular cancer. This comprehensive text also

examines new issues regarding some of the less frequently explored areas of men’s health, such as Tourette’s

syndrome, depression, and cosmetic surgery.

New topics in the Third Edition include:

about the editors...

ROGER S KIRBY is Consultant Urological Surgeon, Professor of Urology, and Director of The Prostate Centre,

London, UK. He has written 59 books and 320 academic papers, is founding Editor of Prostate Cancer and

Prostatic Diseases, and Associate Editor of the British Journal of Urology International. In 2006 he was awarded

the St Peter’s medal, the highest award in British Urology.

CULLEY C CARSON III is Rhodes Distinguished Professor and Chief of Urology, University of North Carolina at

Chapel Hill, Chapel Hill, NC, USA. He trained in urology at the Mayo Clinic Rochester, MN, USA.

Dr. Carson has received several awards, including 2007 Healthcare Heroes and the Neal Award for

editorial writing.

ALAN WHITE is Professor of Men’s Health and Director of the Centre for Men’s Health, Leeds Metropolitan

University, Leeds, UK, and Chair of the Board of Trustees for the Men’s Health Forum. He is the world’s first

Professor of Men’s Health. His research, among others, includes the Scoping Study on Men’s Health and the

Report on the State of Men’s Health across 17 European Countries.

MICHAEL G KIRBY is visiting Professor to the University of Hertfordshire and to The Prostate Centre,

London, UK. He is Editor of Primary Care Cardiovascular and is on the editorial board of many other journals.

Professor Kirby is a member of several NHS Advisory Boards, Fellow of the Royal College of Physicians, and

Associate Member of the British Association of Urological Surgeons.

Printed in India

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Edited by

Roger S Kirby

Culley C Carson III

Alan White

Michael G Kirby

men’s health

Kirby

Carson

White

Kirby

Third

Edition

Male Viagra and drug treatment for impaired sexual function

• colon and bowel cancers • oesophagitis • men and mental

health, including male depression • peptic ulcer • OAB in

men • testosterone and the metabolic syndrome • Tourettes

Syndrome • ADHD • men and sport related injuries • men

and their body image, including body building/steroid abuse

• cosmetic surgery for men • rehabilitation in widowed men •

Male Viagra and drug treatment for impaired sexual function

• colon and bowel cancers • oesophagitis

men’s

health Third Edition

• drug treatments for impaired sexual function

• colon and bowel cancers

• esophagitis

• mental health, including male depression

• peptic ulcer

• overactive bladder in men

• testosterone and the metabolic syndrome

• men and sport-related injuries

• men and their body image

• cosmetic surgery for men

• rehabilitation in widowed men

• Tourette’s syndrome

Kirby_978-0415447331.indd 1 12/2/08 2:21:19 PM

Men’s Health

Men’s Health

Third Edition

Edited by

Roger S Kirby MA MD FRCS(Urol) FEBU

Director

The Prostate Centre

London

UK

Culley C Carson III MD

Division of Urology

University of North Carolina at Chapel Hill

Chapel Hill, NC

USA

Alan White PhD RN

Centre for Men’s Health

Faculty of Health

Leeds Metropolitan University

Leeds

UK

and

Michael G Kirby

Visiting Professor

University of Hertfordshire and the Prostate Centre

London

UK

Dedicated to Professor Ken Kirby FRS

vii

List of contributors xi

Foreword xvii

Roger Boyle

Preface xviii

Roger S Kirby, Culley C Carson III, Michael G Kirby, and Alan White

SECTION 1: MEN AND CANCER 1

1. Men and cancer (epidemiology) 3

Alan White

2. Ignorance and uncertainty regarding cancer and cancer genetics in men 17

Clare Moynihan, Robert Huddart

3. Prostate cancer 27

Roger S Kirby

4. Testicular cancer 39

RTD Oliver

5. Bladder cancer 53

David A Swanson, Paul K Hegarty

6. Colorectal cancer 65

John Northover

7. Penile cancer and associated dermatoses 80

Majid Shabbir, Ben Hughes, and Nick Watkin

8. Cutaneous melanoma 88

Keliegh S Culpepper, Phillip H McKiee

Contents

Contents

viii

SECTION 2: CARDIOVASCULAR RISK REDUCTION IN MEN 103

9. Coronary heart disease in men 105

Henry Purcell

10. Raised blood pressure: the biggest cause of premature death and disability in men? 113

Graham A MacGregor, Feng J He

11. Heart failure 120

John GF Cleland, Alison P Coletta, Klaus KA Witte, and Andrew L Clark

12. Lipids and lipid-modifying therapy 153

Moira MB Mungall, Allan Gaw

13. Erectile dysfunction, cardiovascular risk, and the primary care clinician 163

Louis Kuritzky, Martin M Miner

SECTION 3: SEXUAL HEALTH AND MEN 173

14. Risk factors in men with erectile dysfunction 175

Hemant Solomon

15. Evaluation and treatment of male infertility 191

Joseph Dall’Era, Craig S Niederberger, and Randall B Meacham

16. Effects of testosterone replacement therapy on the prostate in the aging male 199

Michael G Kirby, Melanie E Cunningham, and Frances Bunn

17. Novel approaches to male contraception 211

Richard A Anderson

18. Peyronie’s disease: history and medical therapy 223

J Slade Hubbard, Culley C Carson III

19. Hypospadias: uncovering a common problem 239

Hitendra RH Patel and Christopher RJ Woodhouse

20. HIV infection and AIDS 252

Andrew M Moon, John A Bartlett

21. Sexually transmitted infections 273

Katherine M Coyne, Simon E Barton

22. Circumcision 280

Angus HN Whitfield, Hugh N Whitfield

23. Genital piercing 288

William R Anderson, Simon AV Holmes

SECTION 4: MEN AND CHRONIC CONDITIONS 297

24. Osteoporosis in men 299

Lionel S Lim

Contents

ix

25. Overactive bladder in men 314

Karen E Smith, Karl J Kreder

26. Benign prostatic hyperplasia 325

Tom McNicholas, Charlotte Foley

27. Prostatitis and chronic pelvic pain 337

J Curtis Nickel

28. Androgenetic alopecia 352

Desmond Chia Cin Gan, Rodney Sinclair

29. Diabetes mellitus: focus on type 2 diabetes 368

D John Betteridge

SECTION 5: MEN AND THE GASTRO-INTESTINAL SYSTEM 387

30. Esophagitis and peptic ulcer disease 389

Adam Humphries, Sean Preston

SECTION 6: MEN AND MENTAL/EMOTIONAL HEALTH AND TRAUMA 401

31. Men and mental health 403

Alan Pringle

32. Trauma in male health 413

Tatum Tarin, Simon Kimm, Jack W McAninch, and Daniel Rosenstein

33. Men and suicide: assessment and management in a primary care setting 424

Nick Hervey, Dominique LeTouze

34. Alcohol 431

Brian Wells

SECTION 7: MEN AND THEIR LIFESTYLE 443

35. Exercise and health 445

Roy J Shephard

36. Obesity and men’s health 463

David Haslam

37. Smoking and lung cancer 474

Richard Doll

38. Men as risk takers 484

Rod Griffiths

39. Keeping fit: avoiding and diagnosing chronic soft-tissue injuries 489

David Sutherland Muckle

40. Men’s body image 493

Donald R McCreary

Contents

x

SECTION 8: MISCELLANEOUS TOPICS 503

41. Men and help seeking 505

Alan White, Ian Banks

42. Men’s health in primary care: an emerging paradigm of sexual function and

cardiometabolic risk 515

Martin M Miner, Richard Sadovsky

43. The health of gay men 536

Justin Varney

44. Men at work 545

Steven Boorman

Index 551

xi

Richard A Anderson MD PhD FRCOG

Division of Reproductive and Developmental

Science

University of Edinburgh

Edinburgh, Scotland

UK

William R Anderson MB FRCS(Ed) FRCS(Glas)

Urology Research Fellow

Department of Urology

St Mary’s Hospital

Portsmouth

UK

Ian Banks

Professor of Men’s Health

Leeds Metropolitan University

Leeds

and President

European Men’s Health Forum

London

UK

John A Bartlett

Kilimanjaro Christian Medical Centre

Moshi

Tanzania

and Division of Infectious Diseases

Department of Medicine

Duke University Medical Center

Durham, NC

USA

Simon E Barton BSc MD FRCP(Ed) FRCP

Consultant Physician GUM/HIV

Chelsea & Westminster NHS Foundation Trust

London

UK

D John Betteridge MD PhD

University College London

London

UK

Steven Boorman MBBS MRCGP FFOM FRCP

Director Corporate Responsibility

Chief Medical Adviser

Royal Mail Group

London

UK

Frances Bunn

Faculty of Health and Human Sciences

University of Hertfordshire

Hertfordshire

UK

Culley C Carson III MD

Division of Urology

University of North Carolina at Chapel Hill

Chapel Hill, NC

USA

List of contributors

Contributors

xii

Sir Richard Doll DM Dsc FRCP FRS

Honorary Member, Clinical Trial Service Unit and

Epidemiological Studies Unit

Nuffield Department of Clinical Medicine

University of Oxford

Oxford

UK

Charlotte Foley BM BCh MA MRCS

Department of Urology

Barnet and Chase Farm Hospitals NHS Trust

Barnet General Hospital

Barnet

UK

Desmond Chia Chin Gan MBBS BMedSci

Department of Dermatology

St Vincent’s Hospital

Melbourne

Australia

Allan Gaw MD PhD

Director, Clinical Trials Unit

Glasgow Royal Infirmary

Glasgow, Scotland

UK

Rod Griffiths CBE

Past President

Faculty of Public Health

London

UK

David Haslam MD

General Practitioner

Watton Place Clinic

Watton

Physician in Obesity Medicine

Centre for Obesity Research

Luton & Dunstable Hospital

Luton

and Clinical Director

National Obesity Forum

UK

Feng J He

Blood Pressure Unit

Cardiac and Vascular Sciences

St George’s, University of London

London

UK

Andrew L Clark

University of Hull

Castle Hill Hospital

Kingston-upon-Hull

UK

John GF Cleland

University of Hull

Castle Hill Hospital

Kingston-upon-Hull

UK

Alison P Coletta

Medical Writer

European Journal of Heart Failure

University of Hull

Castle Hill Hospital

Kingston-upon-Hull

UK

Katherine M Coyne BA MRCP

Specialist Registrar GUM/HIV

Chelsea & Westminster NHS Foundation Trust

London

UK

Keliegh S Culpepper MD

Harvard Dermatopathology Fellow

Department of Pathology

Brigham and Women’s Hospital

Harvard Medical School

Boston, MA

USA

Melanie E Cunningham

Faculty of Health and Human Sciences

University of Hertfordshire

Hertfordshire

UK

Joseph Dall’Era MD

Division of Urology

School of Medicine

University of Colorado – Denver

Aurora, CO

USA

Contributors

xiii

Michael G Kirby

Visiting Professor

University of Hertfordshire and the Prostate

Centre

London

UK

Roger S Kirby MA MD FRCS(Urol) FEBU

Director

The Prostate Centre

London

UK

Karl J Kreder MD MBA

Professor and Vice Chair

Department of Urology

University of Iowa

Iowa City, IA

USA

Louis Kuritzky MD

Family Medicine Residency Program

University of Florida

Gainesville, FL

USA

Dominique LeTouze

Southwark Primary Care Trust

Southwark

UK

Lionel S Lim MBBS MPH FACP FACPM

Assistant Clinical Professor of Medicine

Griffin Hospital

Derby, CT

USA

Graham A MacGregor

Blood Pressure Unit

Cardiac and Vascular Sciences

St George’s, University of London

London

UK

Paul K Hegarty

Department of Urology

University of Texas MD Anderson Cancer Center

Houston, TX

USA

Nick Hervey

South London and Maudsley Hospital

London

UK

Simon AV Holmes MB MS FRCS(Urol)

Consultant Urologist

St Mary’s Hospital

Portsmouth

UK

J Slade Hubbard MD

Division of Urology

University of North Carolina at Chapel Hill

Chapel Hill, NC

USA

Robert Huddart

Institute of Cancer Research

and The Royal Marsden Hospital Trust

The Bob Champion Unit

Sutton

UK

Ben Hughes MBBS FRCS

Clinical Research Fellow in Urology

St George’s Hospital

London

UK

Adam Humphries MBBS BSc MRCP

Department of Histopathology

London Research Institute, Cancer Research

and Department of Gastroenterology

St Mary’s Hospital, Imperial College

Healthcare NHS Trust

London

UK

Simon Kimm MD

Urology Resident

Stanford University

Stanford, CA

USA

Contributors

xiv

Andrew M Moon

Kilimanjaro Christian Medical Centre

Duke University Collaboration

Moshi

Tanzania

Clare Moynihan

Research Associate and Senior Research Fellow

Academic Department of Radiotherapy

Institute of Cancer Research

and The Royal Marsden Hospital Trust

The Bob Champion Unit

Sutton

UK

David Sutherland Muckle MD FRCS

Consultant Surgeon in Trauma and Orthopaedics

Medical Adviser to FIFA, UEFA, and The FA.

Examiner, Royal College of Surgeons

Edinburgh

and Park View Medical Clinic

Middlesbrough

UK

Moira MB Mungall MB

Clinical Research Fellow

Glasgow Royal Infirmary

Glasgow, Scotland

UK

J Curtis Nickel MD FRCSC

Professor of Urology

Canada Research Chair in Urologic Pain and

Inflammation

Queen’s University

Kingston General Hospital

Kingston, ON

Canada

Craig S Niederberger MD

Department of Urology

University of Chicago at Illinois

Chicago, IL

USA

John Northover MS FRCS

Professor of Intestinal Surgery

Imperial College

London

UK

Jack W McAninch MD FACS

Professor and Vice Chairman

Department of Urology

University of California

San Francisco General Hospital

San Francisco, CA

USA

Donald R McCreary PhD

Adjunct Professor of Psychology

York University

Toronto, ON

and Brock University

St Catherines, ON

Canada

Phillip H McKee MD

Director, Division of Dermopathology

Brigham and Women’s Hospital

Boston, MA

USA

Tom McNicholas MB BS FRCS FEBU

Consultant Urological Surgeon

Visiting Professor, University of Hertfordshire

Lister Hospital

Hertfordshire

UK

Randall B Meacham MD

Division of Urology

School of Medicine

University of Colorado – Denver

Aurora, CO

USA

Martin M Miner MD

Co-Director Men’s Health Center

The Miriam Hospital

and Associate Clinical Professor of

Family Medicine

The Warren Alpert School of Medicine

Brown University School of Medicine

Providence, RI

USA

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