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about the book…
Edited by ROGER S KIRBY, The Prostate Centre, London, UK; CULLEY C CARSON III, University of North Carolina
School of Medicine, Chapel Hill, NC, USA; MICHAEL G KIRBY, The Prostate Centre, London, UK; and ALAN WHITE,
Leeds Metropolitan University, Leeds, UK
The Third Edition of Men’s Health provides an authoritative reference source for urologists, andrologists,
general practitioners, and all professionals who diagnose and treat male patients with a variety of male health
problems, such as prostate cancer, male osteoporosis, and testicular cancer. This comprehensive text also
examines new issues regarding some of the less frequently explored areas of men’s health, such as Tourette’s
syndrome, depression, and cosmetic surgery.
New topics in the Third Edition include:
about the editors...
ROGER S KIRBY is Consultant Urological Surgeon, Professor of Urology, and Director of The Prostate Centre,
London, UK. He has written 59 books and 320 academic papers, is founding Editor of Prostate Cancer and
Prostatic Diseases, and Associate Editor of the British Journal of Urology International. In 2006 he was awarded
the St Peter’s medal, the highest award in British Urology.
CULLEY C CARSON III is Rhodes Distinguished Professor and Chief of Urology, University of North Carolina at
Chapel Hill, Chapel Hill, NC, USA. He trained in urology at the Mayo Clinic Rochester, MN, USA.
Dr. Carson has received several awards, including 2007 Healthcare Heroes and the Neal Award for
editorial writing.
ALAN WHITE is Professor of Men’s Health and Director of the Centre for Men’s Health, Leeds Metropolitan
University, Leeds, UK, and Chair of the Board of Trustees for the Men’s Health Forum. He is the world’s first
Professor of Men’s Health. His research, among others, includes the Scoping Study on Men’s Health and the
Report on the State of Men’s Health across 17 European Countries.
MICHAEL G KIRBY is visiting Professor to the University of Hertfordshire and to The Prostate Centre,
London, UK. He is Editor of Primary Care Cardiovascular and is on the editorial board of many other journals.
Professor Kirby is a member of several NHS Advisory Boards, Fellow of the Royal College of Physicians, and
Associate Member of the British Association of Urological Surgeons.
Printed in India
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Edited by
Roger S Kirby
Culley C Carson III
Alan White
Michael G Kirby
men’s health
Kirby
•
Carson
•
White
•
Kirby
Third
Edition
Male Viagra and drug treatment for impaired sexual function
• colon and bowel cancers • oesophagitis • men and mental
health, including male depression • peptic ulcer • OAB in
men • testosterone and the metabolic syndrome • Tourettes
Syndrome • ADHD • men and sport related injuries • men
and their body image, including body building/steroid abuse
• cosmetic surgery for men • rehabilitation in widowed men •
Male Viagra and drug treatment for impaired sexual function
• colon and bowel cancers • oesophagitis
men’s
health Third Edition
• drug treatments for impaired sexual function
• colon and bowel cancers
• esophagitis
• mental health, including male depression
• peptic ulcer
• overactive bladder in men
• testosterone and the metabolic syndrome
• men and sport-related injuries
• men and their body image
• cosmetic surgery for men
• rehabilitation in widowed men
• Tourette’s syndrome
Kirby_978-0415447331.indd 1 12/2/08 2:21:19 PM
Men’s Health
Men’s Health
Third Edition
Edited by
Roger S Kirby MA MD FRCS(Urol) FEBU
Director
The Prostate Centre
London
UK
Culley C Carson III MD
Division of Urology
University of North Carolina at Chapel Hill
Chapel Hill, NC
USA
Alan White PhD RN
Centre for Men’s Health
Faculty of Health
Leeds Metropolitan University
Leeds
UK
and
Michael G Kirby
Visiting Professor
University of Hertfordshire and the Prostate Centre
London
UK
Dedicated to Professor Ken Kirby FRS
vii
List of contributors xi
Foreword xvii
Roger Boyle
Preface xviii
Roger S Kirby, Culley C Carson III, Michael G Kirby, and Alan White
SECTION 1: MEN AND CANCER 1
1. Men and cancer (epidemiology) 3
Alan White
2. Ignorance and uncertainty regarding cancer and cancer genetics in men 17
Clare Moynihan, Robert Huddart
3. Prostate cancer 27
Roger S Kirby
4. Testicular cancer 39
RTD Oliver
5. Bladder cancer 53
David A Swanson, Paul K Hegarty
6. Colorectal cancer 65
John Northover
7. Penile cancer and associated dermatoses 80
Majid Shabbir, Ben Hughes, and Nick Watkin
8. Cutaneous melanoma 88
Keliegh S Culpepper, Phillip H McKiee
Contents
Contents
viii
SECTION 2: CARDIOVASCULAR RISK REDUCTION IN MEN 103
9. Coronary heart disease in men 105
Henry Purcell
10. Raised blood pressure: the biggest cause of premature death and disability in men? 113
Graham A MacGregor, Feng J He
11. Heart failure 120
John GF Cleland, Alison P Coletta, Klaus KA Witte, and Andrew L Clark
12. Lipids and lipid-modifying therapy 153
Moira MB Mungall, Allan Gaw
13. Erectile dysfunction, cardiovascular risk, and the primary care clinician 163
Louis Kuritzky, Martin M Miner
SECTION 3: SEXUAL HEALTH AND MEN 173
14. Risk factors in men with erectile dysfunction 175
Hemant Solomon
15. Evaluation and treatment of male infertility 191
Joseph Dall’Era, Craig S Niederberger, and Randall B Meacham
16. Effects of testosterone replacement therapy on the prostate in the aging male 199
Michael G Kirby, Melanie E Cunningham, and Frances Bunn
17. Novel approaches to male contraception 211
Richard A Anderson
18. Peyronie’s disease: history and medical therapy 223
J Slade Hubbard, Culley C Carson III
19. Hypospadias: uncovering a common problem 239
Hitendra RH Patel and Christopher RJ Woodhouse
20. HIV infection and AIDS 252
Andrew M Moon, John A Bartlett
21. Sexually transmitted infections 273
Katherine M Coyne, Simon E Barton
22. Circumcision 280
Angus HN Whitfield, Hugh N Whitfield
23. Genital piercing 288
William R Anderson, Simon AV Holmes
SECTION 4: MEN AND CHRONIC CONDITIONS 297
24. Osteoporosis in men 299
Lionel S Lim
Contents
ix
25. Overactive bladder in men 314
Karen E Smith, Karl J Kreder
26. Benign prostatic hyperplasia 325
Tom McNicholas, Charlotte Foley
27. Prostatitis and chronic pelvic pain 337
J Curtis Nickel
28. Androgenetic alopecia 352
Desmond Chia Cin Gan, Rodney Sinclair
29. Diabetes mellitus: focus on type 2 diabetes 368
D John Betteridge
SECTION 5: MEN AND THE GASTRO-INTESTINAL SYSTEM 387
30. Esophagitis and peptic ulcer disease 389
Adam Humphries, Sean Preston
SECTION 6: MEN AND MENTAL/EMOTIONAL HEALTH AND TRAUMA 401
31. Men and mental health 403
Alan Pringle
32. Trauma in male health 413
Tatum Tarin, Simon Kimm, Jack W McAninch, and Daniel Rosenstein
33. Men and suicide: assessment and management in a primary care setting 424
Nick Hervey, Dominique LeTouze
34. Alcohol 431
Brian Wells
SECTION 7: MEN AND THEIR LIFESTYLE 443
35. Exercise and health 445
Roy J Shephard
36. Obesity and men’s health 463
David Haslam
37. Smoking and lung cancer 474
Richard Doll
38. Men as risk takers 484
Rod Griffiths
39. Keeping fit: avoiding and diagnosing chronic soft-tissue injuries 489
David Sutherland Muckle
40. Men’s body image 493
Donald R McCreary
Contents
x
SECTION 8: MISCELLANEOUS TOPICS 503
41. Men and help seeking 505
Alan White, Ian Banks
42. Men’s health in primary care: an emerging paradigm of sexual function and
cardiometabolic risk 515
Martin M Miner, Richard Sadovsky
43. The health of gay men 536
Justin Varney
44. Men at work 545
Steven Boorman
Index 551
xi
Richard A Anderson MD PhD FRCOG
Division of Reproductive and Developmental
Science
University of Edinburgh
Edinburgh, Scotland
UK
William R Anderson MB FRCS(Ed) FRCS(Glas)
Urology Research Fellow
Department of Urology
St Mary’s Hospital
Portsmouth
UK
Ian Banks
Professor of Men’s Health
Leeds Metropolitan University
Leeds
and President
European Men’s Health Forum
London
UK
John A Bartlett
Kilimanjaro Christian Medical Centre
Moshi
Tanzania
and Division of Infectious Diseases
Department of Medicine
Duke University Medical Center
Durham, NC
USA
Simon E Barton BSc MD FRCP(Ed) FRCP
Consultant Physician GUM/HIV
Chelsea & Westminster NHS Foundation Trust
London
UK
D John Betteridge MD PhD
University College London
London
UK
Steven Boorman MBBS MRCGP FFOM FRCP
Director Corporate Responsibility
Chief Medical Adviser
Royal Mail Group
London
UK
Frances Bunn
Faculty of Health and Human Sciences
University of Hertfordshire
Hertfordshire
UK
Culley C Carson III MD
Division of Urology
University of North Carolina at Chapel Hill
Chapel Hill, NC
USA
List of contributors
Contributors
xii
Sir Richard Doll DM Dsc FRCP FRS
Honorary Member, Clinical Trial Service Unit and
Epidemiological Studies Unit
Nuffield Department of Clinical Medicine
University of Oxford
Oxford
UK
Charlotte Foley BM BCh MA MRCS
Department of Urology
Barnet and Chase Farm Hospitals NHS Trust
Barnet General Hospital
Barnet
UK
Desmond Chia Chin Gan MBBS BMedSci
Department of Dermatology
St Vincent’s Hospital
Melbourne
Australia
Allan Gaw MD PhD
Director, Clinical Trials Unit
Glasgow Royal Infirmary
Glasgow, Scotland
UK
Rod Griffiths CBE
Past President
Faculty of Public Health
London
UK
David Haslam MD
General Practitioner
Watton Place Clinic
Watton
Physician in Obesity Medicine
Centre for Obesity Research
Luton & Dunstable Hospital
Luton
and Clinical Director
National Obesity Forum
UK
Feng J He
Blood Pressure Unit
Cardiac and Vascular Sciences
St George’s, University of London
London
UK
Andrew L Clark
University of Hull
Castle Hill Hospital
Kingston-upon-Hull
UK
John GF Cleland
University of Hull
Castle Hill Hospital
Kingston-upon-Hull
UK
Alison P Coletta
Medical Writer
European Journal of Heart Failure
University of Hull
Castle Hill Hospital
Kingston-upon-Hull
UK
Katherine M Coyne BA MRCP
Specialist Registrar GUM/HIV
Chelsea & Westminster NHS Foundation Trust
London
UK
Keliegh S Culpepper MD
Harvard Dermatopathology Fellow
Department of Pathology
Brigham and Women’s Hospital
Harvard Medical School
Boston, MA
USA
Melanie E Cunningham
Faculty of Health and Human Sciences
University of Hertfordshire
Hertfordshire
UK
Joseph Dall’Era MD
Division of Urology
School of Medicine
University of Colorado – Denver
Aurora, CO
USA
Contributors
xiii
Michael G Kirby
Visiting Professor
University of Hertfordshire and the Prostate
Centre
London
UK
Roger S Kirby MA MD FRCS(Urol) FEBU
Director
The Prostate Centre
London
UK
Karl J Kreder MD MBA
Professor and Vice Chair
Department of Urology
University of Iowa
Iowa City, IA
USA
Louis Kuritzky MD
Family Medicine Residency Program
University of Florida
Gainesville, FL
USA
Dominique LeTouze
Southwark Primary Care Trust
Southwark
UK
Lionel S Lim MBBS MPH FACP FACPM
Assistant Clinical Professor of Medicine
Griffin Hospital
Derby, CT
USA
Graham A MacGregor
Blood Pressure Unit
Cardiac and Vascular Sciences
St George’s, University of London
London
UK
Paul K Hegarty
Department of Urology
University of Texas MD Anderson Cancer Center
Houston, TX
USA
Nick Hervey
South London and Maudsley Hospital
London
UK
Simon AV Holmes MB MS FRCS(Urol)
Consultant Urologist
St Mary’s Hospital
Portsmouth
UK
J Slade Hubbard MD
Division of Urology
University of North Carolina at Chapel Hill
Chapel Hill, NC
USA
Robert Huddart
Institute of Cancer Research
and The Royal Marsden Hospital Trust
The Bob Champion Unit
Sutton
UK
Ben Hughes MBBS FRCS
Clinical Research Fellow in Urology
St George’s Hospital
London
UK
Adam Humphries MBBS BSc MRCP
Department of Histopathology
London Research Institute, Cancer Research
and Department of Gastroenterology
St Mary’s Hospital, Imperial College
Healthcare NHS Trust
London
UK
Simon Kimm MD
Urology Resident
Stanford University
Stanford, CA
USA
Contributors
xiv
Andrew M Moon
Kilimanjaro Christian Medical Centre
Duke University Collaboration
Moshi
Tanzania
Clare Moynihan
Research Associate and Senior Research Fellow
Academic Department of Radiotherapy
Institute of Cancer Research
and The Royal Marsden Hospital Trust
The Bob Champion Unit
Sutton
UK
David Sutherland Muckle MD FRCS
Consultant Surgeon in Trauma and Orthopaedics
Medical Adviser to FIFA, UEFA, and The FA.
Examiner, Royal College of Surgeons
Edinburgh
and Park View Medical Clinic
Middlesbrough
UK
Moira MB Mungall MB
Clinical Research Fellow
Glasgow Royal Infirmary
Glasgow, Scotland
UK
J Curtis Nickel MD FRCSC
Professor of Urology
Canada Research Chair in Urologic Pain and
Inflammation
Queen’s University
Kingston General Hospital
Kingston, ON
Canada
Craig S Niederberger MD
Department of Urology
University of Chicago at Illinois
Chicago, IL
USA
John Northover MS FRCS
Professor of Intestinal Surgery
Imperial College
London
UK
Jack W McAninch MD FACS
Professor and Vice Chairman
Department of Urology
University of California
San Francisco General Hospital
San Francisco, CA
USA
Donald R McCreary PhD
Adjunct Professor of Psychology
York University
Toronto, ON
and Brock University
St Catherines, ON
Canada
Phillip H McKee MD
Director, Division of Dermopathology
Brigham and Women’s Hospital
Boston, MA
USA
Tom McNicholas MB BS FRCS FEBU
Consultant Urological Surgeon
Visiting Professor, University of Hertfordshire
Lister Hospital
Hertfordshire
UK
Randall B Meacham MD
Division of Urology
School of Medicine
University of Colorado – Denver
Aurora, CO
USA
Martin M Miner MD
Co-Director Men’s Health Center
The Miriam Hospital
and Associate Clinical Professor of
Family Medicine
The Warren Alpert School of Medicine
Brown University School of Medicine
Providence, RI
USA