Nghiên cứu rối loạn lipid máu và các yếu tố nguy cơ ở bệnh nhân tiền đái tháo đường

TAP CHi Y HOC VIET NAM TAP 463 - THANG 2 - SO 1 - 2018

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NGHIEN Ciru ROI LOAN LIPID MAU VA CAC YEU TO NGUY Cff

6* BENH NHAN TIEN DAI THAO DirCTNG

TOM TAT

Muc tieu: Nghien ciiU dac diem lam sang va cac

yeu to nguy cO d benh nhan tien dai thao du'dng; Ty

le, mdc dp rdi loan lipid mau 6 benh nhan tien dai

thao di/dng. Doi tu'dng va phu'dng phap: Nghien

CLfU tien CLTU, mo ta cat ngang cd doi chung 160 benh

nhan tien dai thao du'dng. Ket qua: Chi sd vong

bung, ty le vong eo tren vong mong, chi so khdi cd

the d nhdm benh cao hdn so vdi nhdm chirng. Ty le

rw loan li^id mau d nhom benh cao hdn nhom chuhg.

Trong nhom benh, cac chi so roi loan lipid mau cao

nhat d phan nhdm dai thao du'dng, den nhom roi loan

dung nap glucose mau va thap nhat 6 nhom dung nap

glucose mau binh ttiu'dng. Ket luan: Cac yeu to nguy

cd d nhdm benh cao hdn nhdm chu'ng. Ty If roi loan

lipid mau d nhom tienh cao hdn nhom chulig va ty le, cac

chi so roi ban lipid mau cao nhat d phan nhdm dai thao

du'dng, dai nhdm rS toan dung nap glucose mau va thap

nhat d nhom dung nap glucose mau bmh thu'dng.

Tir'fc/tda:Roi loan diuyen hda lipid, fen dai thao dUdng,

SUMMARY

RESEARCH OF LIPID BLOOD DISORDERS

AND RISK FACTORS IN PRE-DIABEHC PATIEIVTS

Objective: Study of clinical charactenstics and

risk factors in pre-diabetic patients; Rate, level of

dyslipidemia in pre-diabetic patients. Subjects and

methods: A prospective, cross-sectional study of 150

pre-diabetic patients. Results: The waist

circumference, waist circumference on the buttocks,

body mass index was higher in the control group t^an

the control group. The prevalence of dyslipidemia was

higher in the control group. In the group of patients,

the hyperlipidemia was highest in the diabetic

*Benh vien Quan y4' Nghe An

Chiu trach nhiem chi'nh: Nguyen Tnjng Kien

Email: trung [email protected]

Ngay nhan bai: 30/12/2017

Ngay phan bien khoa hpc: 26/1/2018

Ngay duyet bai: 3/2/2018

Nguyen Trung Kien*

subgroups, the lowest in the glucose tolerance group

and the lowest in the glucose tolerance group normal

blood. Conclusions: Risk factors were Jiigher in the

control group than in the control group. The

prevalence of dyslipidemia was higher m the control

and treatment groups, the highest lipid abnormalities

in the diabetic subgroup, the lowest In the blood

glucose tolerance group, and the lowest in the blood

glucose tolerance group normal.

/fe/ivo/i/s; Dyslipidemia, pre-diabetes

I. DAT VAN OE

Rdi loan lipid mau la tinh trang thay ddi mgt

hay nhieu thanh phan lipid mau, la mot trong cac

yeu to nguy cd benh ly tim mach. 6 My, theo

NCEP - ATP II jiam 1993 thi 25% ngu'di tru'dng

thanh tCr 20 tudi trd len cd cholesterol toan phan

>6,2mmol/l. a Viet Nam cd khoang 26% ngu'di

d lira tuoi 25-74 mac rdi loan lipid mau. Rdi loan

lipid mau, tang huyet ap, tien dai thao du'dng,

dai thao du'dng lien quan chat che vdi nhau.

Tir nam 2002 khai niem tien dai thao du'dng

ra ddi de chi tinh trang du'dng huyet cao hdn

mij'c binh thu'dng nhu'ng chu^ den miJc chan

doan benh dai thao du'dng (DTB). Tien OTO la

tinh trang suy giam chuyen hda glucose, bao

gom 2 tinh huong: Roi loan glucose mau luc ddi

(RLGLD - Impaired Fasting Glucose- IFG) va roi

loan dung nap glucose (RLDNG). Ca hai tinh

huong nay dSu tang glucose mau, nhu'ng chuia

dat mire chan doan DT£) thu'c sy". Tuy nhien d

giai doan nay da xuat hien tinh trang khang

Insulin, la bu'dc khdi dau trong tien trinh xuat

hien DTD type 2 vdi ty le chuyen doi hang nam

tir 5% -10%.

Ty le mac benh dai thao du'dng dang gia tang

tren toan the gidi va du" kien rang > 470 trieu

ngu'di se ed tien dai thao du'dng trong nam 2030.