Nanoparticles:synthesis and applications on life science and environmental technology

l O P Publishing j Vietnam Academy of Science and Technology Advances in Natural Sciences' Nanoscience and Nanotechnology

Adv NaL Sci: Nanosci. Nanotechnoi 6 (2015) 015008 <9pp) doi.10.1088/2043-6262/6/1/015008

Nanoparticles: synthesis and applications in

life science and environmental technology*

Hoang Luong Nguyen^ Hoang Nam Nguyen^'^, Hoang Hai Nguyen^

Manh Quynh Luu^ and Minh Hieu Nguyen^

' Nano and Energy Center, Hanoi University of Science, Vietnam National University in Hanoi, 334

Nguyen Trai, Thanh Xuan, Hanoi, Vietnam

^Center for Materials Science, Faculty of Physics, Hanoi University of Science, Vietnam National

University m Hanoi, 334 Nguyen Trai, Thanh Xuan, Hanoi, Vietnam

E-mail' [email protected]

Received 20 October 2014

Accepted for publication 12 November 2014

Published 31 December 2014

CrossMark

Abstract

This work focuses on the synthesis, functionalization, and application of gold and silver

nanoparticles, magnetic nanoparticles Fe304, combination of 4-ATP-coated silver nanoparticles

and FcsOd nanoparticles. The synthesis methods such as chemical reduction, seeding,

coprecipitation,and inverse microemulsion will be outUned. Sihca- and amino-coated

nanoparticles are suitable for several apphcations in biomedicine and the environment. The

applications of the prepared nanoparticles for early detection of breast cancer cells, basal cell

carcinoma, antibacterial test, arsenic removal from water. Herpes DNA separation, CD4"^ cell

separation and isolation of DNA of Hepatitis virus type B (HBV) and Epslem-Barr vtius (EBV)

are discussed. Finally, some promising perspectives will be pointed out.

Keywords: gold nanoparticles, silver nanoparticles, magnetic nanoparticles, fimctionaUzation

Madiematics Subject Classification: 4.02

1. Introduction also be engineered to actively interact with a pollutant and

treat them.

Nanoparticles are of great interest because of their technolo- In this work we focus on the synthesis, functionalization,

gical and fundamental scientific importance. These matenals and apphcation of gold and silver nanoparticles, magnetic

often exhibit fascinating properties which cannot be achieved nanoparticles Fe304, combination of 4-ammothiophenol (4-

by theu* bulk counterparts. Their applications, or potential ATP)-coated silver nanoparticles and Fe304 nanoparticles.

applications, are in many fields [1-5 and references therein].

Nanoparticles have advantages in application in life science

and the environment. Theu- particle size is comparable with

the dimension of small molecules (about 1-10 nm) or of 2. Experimental

viruses (about 10-100 nm). This allows nanoparticles to

anach to biological entities without changing their functions. 2.1. Synthesis of nanoparticles

Largs surface area of nanoparticles permits strong bonds will, ^ , , g^,^ nanoparticles. Gold nanoparticles with a size of

surfactant molecules. In dre environment, the small size of ^^^„, ^^ ^ ^^^^ ^^^„ synthesized by a chemical reduction

nanoparticles. together widi Uieir large surface aiea can lead ^^^^ ^^^^ ^^^^ borohydnde (NBR.) [6]. HAuCU and

to very sensitive detection of a specific contaminant from the ^gj ^ ^ ^,j ^ .^ ,^^^^ ,^.^ appropriate time and Ote ratio

presence of which pollution often anses. Nanoparticles can c , , _,- L L j j ,^ ,j • , -, .

i" '^ *^ of gold to sodium borohydnde. Gold nanoparticles with sizes ranging from 2 to 5 nm were also prepared by seeding method * Invited talk at the 7ih Tntemational Workshop on Advanced Materials . _r . . c . i^ - .L i

Science and Nanotechnology IWAMSN2014. 2-6 November, 2014, Ha "^""^ Surfactant of cetyltnmethylamonium bromide

Long. Viemam. (CTAB) [7].

2043.6262/15/01500B+09S33.00 1 © 2015 Vietnam Academy of Science & Technology

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