CHUẨN ĐOÁN ĐIỀU TRỊ BƯỚU ĐẠI BÀO XƯƠNG pdf

Hoäi Chaán thöông Chænh hình Tp. Hoà Chí Minh

84

BÖÔÙU ÑAÏI BAØO XÖÔNG: CHAÅN ÑOAÙN VAØ ÑIEÀU TRÒ

Nguyeãn vaên Thaéng*, Leâ Chí Duõng**

1. TOÙM TAÉT

Toång quan: Böôùu ñaïi baøo xöông

(BÑBX) chieám khoaûng 15% böôùu xöông

nguyeân phaùt. Hôn 75% BÑBX coù vò trí ñaàu

caùc xöông daøi.

Vaät lieäu vaø Phöông phaùp nghieân cöùu:

Qua nghieân cöùu 332 tröôøng hôïp BÑBX ñieàu

trò taïi Khoa Beänh hoïc, Beänh vieän Chaán

thöông chænh hình (CTCH), Thaønh phoá Hoà

Chí Minh töø (11/1991 – 8/2006). Phöông

phaùp nghieân cöùu: tieàn cöùu.

Keát quaû: chuùng toâi ghi nhaän: Beänh

nhaân phaân boá töø 16 – 86 tuoåi, xuaát ñoä cao

ôû tuoåi töø 20 – 40: (67,5%). Beänh gaëp ôû nöõ

nhieàu hôn nam ((nöõ/nam =1/0,93). Tyû leä

taùi phaùt chung laø 9,1%(30 ca). Tyû leä taùi

phaùt phuï thuoäc nhieàu vaøo phöông phaùp

ñieàu trò: Phaãu thuaät caét naïo böôùu vaø gheùp

xöông laø 22,5% (9/40 ca). Phaãu Thuaät caét

naïo böôùu vaø ñoå xi maêng vaø gheùp xöông laø

11,3% (11/97 ca). Phaãu thuaät caét roäng,

gheùp xöông vaø keát hôïp xöông coù laø 5,6%

(9/160 ca). Phaãu thuaät ñoaïn chi laø 3%

(1/33 ca). 2 ca hoùa aùc vaø di caên phoåi

(chieám tyû leä 0,6%).

Keát luaän: BÑBX laø böôùu laønh nhöng

thöôøng taán coâng taïi choã. Tyû leä taùi phaùt cuûa

BÑBX phuï thuoäc nhieàu vaøo phöông phaùp

ñieàu trò.

1. SUMMARY

Background: Giant cell tumor (GCT)

0f the bone, accounts for about 15 percent

of biopsied primary bone tumors. More

than 75 percent of GCT are located near

the articular end of a tubular bone.

Material and Method: We have

studied 332 cases GCT 0f the bone, treated

at the department of orthopedic disease

and oncology, Hospital for traumatology

and orthopedies in HochiMinh city (from

november 1991 to august 2006)

Results: - Incidence: The patients

range from 16 – 86 years of age. The

incidence peak is from 20 to 40 years of

age (67.5%). Female sexual predilection

(F/M = 1/0.93). - Recurrence rate was 9.1

percent (30 cases). Recurrence depended

on method of treatment: 22,5 percent (9

cases) of recurrence GCT if treated by

resection-curettage and bone grafting (40

cases). 11.3 percent (11 cases) of

recurrence GCT if treated by resection￾curettage and cement and bone grafting

(97 cases). 5.6 percent (9 cases) of

recurrence GCT if treated by wide

resection and bone grafting (160 cases). 3

percent (1 cases) of recurrence GCT if

treated by amputation (33 cases).

Malignant transformation and pulmonary

metastasis 2 cases (0.6%).

Conclusions: GCT is a benign tumor

but often locally aggressive. Recurrence rate

GCT depended on method of treatment.

*

Giaûng vieân Ñaïi hoïc Y Döôïc, TP. HCM

** Beänh vieän Chaán thöông chænh hình, TP. HCM