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Cancer sourcebook for women
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Omnigraphics’ Health Reference Series
Helping the Layperson Understand, Manage,
and Avoid Serious Illness
Omnigraphics’ Health Reference Series is designed for the general reader
seeking guidance on how to avoid serious illness by following preventive
lifestyles and recognizing early warning signs. It also supports the layperson
who has received a diagnosis of a serious disease or disorder as well as the
family member or nonprofessional caregiver who must learn to care and
to cope with the illness. Each volume in the series deals comprehensively
with a particular area of medical concern and contains material found in
publications issued by the National Institutes of Health and other agencies
and associations. Nowhere else can general readers find this information
conveniently collected, coordinated, and indexed in book form.
Cancer Sourcebook for Women, Fourth Edition
According to the National Cancer Institute, cancer continues to take a
devastating toll. Among women in the United States, cancer is the secondleading cause of death after heart disease. Medical researchers fighting
against cancer have made significant progress, however. In recent years,
cancer incidence rates have been stable, and—although the annual rate of
decline in cancer death rates among men have been twice as large as the
declines in women—mortality has decreased for ten of the top 15 cancers
in women. With improved cancer screening programs and innovative treatments, women receiving a cancer diagnosis today have a better chance of
overcoming their disease than ever before.
Cancer Sourcebook for Women, Fourth Edition offers updated information
about gynecologic cancers and other cancers of special concern to women,
including breast cancer, cancers of the female reproductive organs, and
cancers responsible for the highest number of deaths in women. It explains
cancer risks—including lifestyle factors, inherited genetic abnormalities, and
hormonal medications—and methods used to diagnose and treat cancer.
Practical suggestions for coping with the treatment side effects are provided,
and a section on cancer survivorship discusses methods for maintaining
quality of life during and after treatment. The book concludes with a glossary
of cancer-related terms, a directory of resources, and facts about locating
support groups.
P.O. Box 31-1640
Detroit, MI 48231
Phone: 800-234-1340
Fax: 800-875-1340
www.omnigraphics.com
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Fourth Edition
Cancer
Sourcebook
for Women
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Cancer
Sour
cebook
for Women
Bellenir
Omnigraphics
Health
Reference
Series
4th Edition
■
Basic Consumer Health Information about Gynecologic
Cancers and Other Cancers of Special Concern to Women,
Including Cancers of the Breast, Cervix, Colon, Lung,
Ovaries, Thyroid, and Uterus
Along with Facts about Benign Conditions of the
Female Reproductive System, Cancer Risk Factors,
Screening and Prevention Programs, Women’s Issues in
Cancer Treatment and Survivorship, Research Initiatives,
a Glossary of Cancer Terms, and a Directory of Resources
for Additional Help and Information
Edited by
Karen Bellenir
Health Reference Series
ISBN 978-0-7808-1139-3
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N
Cancer
SOURCEBOOK
for Women
Fourth Edition
N
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Health Reference Series
Fourth Edition
Cancer
SOURCEBOOK
for Women
N
Basic Consumer Health Information about Gynecologic
Cancers and Other Cancers of Special Concern to Women,
Including Cancers of the Breast, Cervix, Colon, Lung,
Ovaries, Thyroid, and Uterus
Along with Facts about Benign Conditions of the
Female Reproductive System, Cancer Risk Factors,
Screening and Prevention Programs, Women’s Issues
in Cancer Treatment and Survivorship, Research
Initiatives, a Glossary of Cancer Terms, and a
Directory of Resources for Additional Help
and Information
N
Edited by
Karen Bellenir
P.O. Box 31-1640, Detroit, MI 48231
Bibliographic Note
Because this page cannot legibly accommodate all the copyright notices, the Bibliographic
Note portion of the Preface constitutes an extension of the copyright notice.
Edited by Karen Bellenir
Health Reference Series
Karen Bellenir, Managing Editor
David A. Cooke, MD, FACP, Medical Consultant
Elizabeth Collins, Research and Permissions Coordinator
Cherry Edwards, Permissions Assistant
EdIndex, Services for Publishers, Indexers
* * *
Omnigraphics, Inc.
Matthew P. Barbour, Senior Vice President
Kevin M. Hayes, Operations Manager
* * *
Peter E. Ruffner, Publisher
Copyright © 2010 Omnigraphics, Inc.
ISBN 978-0-7808-1139-3
Electronic or mechanical reproduction, including photography, recording, or any other information storage and retrieval system for the purpose of resale is strictly prohibited without
permission in writing from the publisher.
The information in this publication was compiled from the sources cited and from other
sources considered reliable. While every possible effort has been made to ensure reliability,
the publisher will not assume liability for damages caused by inaccuracies in the data,
and makes no warranty, express or implied, on the accuracy of the information contained
herein.
This book is printed on acid-free paper meeting the ANSI Z39.48 Standard. The infinity
symbol that appears above indicates that the paper in this book meets that standard.
Printed in the United States
Library of Congress Cataloging-in-Publication Data
Cancer sourcebook for women : basic consumer health information about
gynecologic cancers and other cancers of special concern to women, including
cancers of the breast, cervix, colon, lung, ovaries, thyroid, and uterus;
along with facts about benign conditions of the female reproductive system,
cancer risk factors, screening and prevention programs, women's issues in
cancer treatment ... / edited by Karen Bellenir. -- 4th ed.
p. cm.
Summary: "Provides basic consumer health information about risk factors,
prevention, diagnosis, and treatment of cancers of concern to women.
Includes index, glossary of related terms, and other resources"--Provided by
publisher.
Includes bibliographical references and index.
ISBN 978-0-7808-1139-3 (hardcover : alk. paper) 1. Generative organs,
Female--Popular works. 2. Cancer in women--Popular works. I. Bellenir,
Karen.
RC280.G5C34 2010
616.99'40082--dc22
2010027636
Table of Contents
Visit www.healthreferenceseries.com to view A Contents Guide to the
Health Reference Series, a listing of more than 15,000 topics and the
volumes in which they are covered.
v
Preface .......................................................................................... xiii
Part I: Understanding Cancer Risks in Women
Chapter 1—What Women Need to Know about Cancer ............... 3
Chapter 2—Common Gynecologic Conditions That
Are Not Indicative of Cancer ................................... 13
Chapter 3—Does Cancer Run in Your Family? ........................... 27
Chapter 4—What Women Need to Know about Smoking
and Cancer Risk ....................................................... 35
Section 4.1—Smoking and Cancer ...................... 36
Section 4.2—Questions and Answers ................. 39
about Women and Smoking
Section 4.3—Smoking Cessation ......................... 42
Chapter 5—Facts about Human Papillomavirus (HPV)
and Cancer Risk ....................................................... 47
Section 5.1—HPV Facts ....................................... 48
Section 5.2—HPV Prevalence in
U.S. Women ..................................... 52
Section 5.3—Questions and Answers about
the HPV Vaccine ............................. 54
vi
Chapter 6—Cancer Risks Associated with
Hormonal Medications ........................................... 63
Section 6.1—Oral Contraceptives
and Cancer Risk ......................... 64
Section 6.2—Menopausal Hormone
Replacement Therapy
Use and Cancer .......................... 68
Section 6.3—Diethylstilbestrol Exposure
and Cancer Risk ......................... 76
Part II: Breast Cancer
Chapter 7—What You Need to Know about
Breast Cancer ......................................................... 85
Chapter 8—Understanding the Risk
of Breast Cancer ..................................................... 97
Section 8.1—Probability of Breast Cancer
in American Women ................... 98
Section 8.2—Breast Cancer Risk and
Protective Factors..................... 100
Section 8.3—Alcohol and Breast Cancer
Risk ........................................... 105
Chapter 9—Genes Associated with Breast Cancer ................. 109
Chapter 10—Breast Cancer Screening...................................... 125
Chapter 11—Staging and Treating Breast Cancer................... 131
Chapter 12—Breast Cancer Treatment and Pregnancy........... 141
Part III: Gynecologic Cancers
Chapter 13—Cervical Cancer..................................................... 149
Section 13.1—Understanding
Cervical Cancer ........................ 150
Section 13.2—How Does Your Doctor
Know You Have Cervical
Cancer? ..................................... 154
Section 13.3—Staging and Treating
Cervical Cancer ........................ 162
vii
Chapter 14—Endometrial Cancer.............................................. 167
Section 14.1—Understanding
Endometrial Cancer................. 168
Section 14.2—Endometrial Cancer
Screening .................................. 172
Section 14.3—Staging and Treating
Endometrial Cancer................. 174
Chapter 15—Gestational Trophoblastic
Tumors .................................................................. 181
Chapter 16—Ovarian Cancer..................................................... 187
Section 16.1—What You Need to Know
about Ovarian Cancer.............. 188
Section 16.2—Ovarian Germ Cell
Tumors...................................... 197
Section 16.3—Ovarian Epithelial
Cancer....................................... 202
Section 16.4—Ovarian Low Malignant
Potential Tumors...................... 205
Section 16.5—Oral Contraceptives
Reduce Long-Term Risk
of Ovarian Cancer .................... 208
Section 16.6—Ovarian Epithelial
Tumors Traced to
Fallopian Tubes ........................ 210
Section 16.7—Removal of Ovaries
and Fallopian Tubes
Cuts Cancer Risk for
BRCA1/2 Carriers .................... 211
Chapter 17—Uterine Cancer...................................................... 213
Section 17.1—Understanding Cancer
of the Uterus............................. 214
Section 17.2—Staging and Treating
Uterine Sarcoma ...................... 217
Chapter 18—Vaginal Cancer...................................................... 223
Chapter 19—Vulvar Cancer ....................................................... 231
viii
Part IV: Other Cancers of Special Concern to Women
Chapter 20—Anal Cancer........................................................... 241
Chapter 21—Colorectal Cancer.................................................. 247
Section 21.1—Cancers of the Colon
and Rectum............................... 248
Section 21.2—Staging and Treating
Cancer of the Colon.................. 252
Section 21.3—Staging and Treating
Cancer of the Rectum............... 258
Chapter 22—Gallbladder and Bile Duct Cancer....................... 263
Chapter 23—Lung Cancer.......................................................... 273
Section 23.1—What You Need to Know
about Lung Cancer................... 274
Section 23.2—Staging and Treating Small
Cell Lung Cancer...................... 279
Section 23.3—Staging and Treating
Non-Small Cell Lung Cancer... 283
Chapter 24—Pancreatic Cancer................................................. 289
Section 24.1—What You Need to Know
about Pancreatic Cancer.......... 290
Section 24.2—Staging and Treating
Pancreatic Cancer .................... 294
Chapter 25—Skin Cancer........................................................... 299
Section 25.1—Facts about Skin Cancer.......... 300
Section 25.2—Can Skin Cancer Be
Prevented? ................................ 305
Section 25.3—Diagnosing and Treating
Melanoma ................................. 308
Section 25.4—Diagnosing and Treating
Non-Melanoma Skin Cancers ... 313
Chapter 26—Thyroid Cancer ..................................................... 319
Section 26.1—What You Need to Know
about Thyroid Cancer............... 320
Section 26.2—Staging and Treating
Thyroid Cancer......................... 325
ix
Part V: Diagnosing and Treating Cancer
Chapter 27—You and Your Healthcare Team............................ 335
Section 27.1—How to Find a Doctor
or Treatment Facility
If You Have Cancer................... 336
Section 27.2—How to Be a Proactive
Patient....................................... 345
Section 27.3—How to Get a Second
Opinion ..................................... 349
Chapter 28—Diagnosing Cancer................................................ 351
Section 28.1—Commonly Used Diagnostic
Tests and Procedures ............... 352
Section 28.2—What to Expect During
a Biopsy..................................... 356
Section 28.3—Colposcopy ................................ 360
Section 28.4—Loop Electrosurgical
Excision Procedure................... 364
Section 28.5—Questions and Answers
about Tumor Markers .............. 367
Chapter 29—What Do Your Cancer Test Results Mean?.......... 371
Section 29.1—Understanding a Pathology
Report ....................................... 372
Section 29.2—Questions and Answers
about Cancer Staging............... 376
Section 29.3—Questions and Answers
about Tumor Grades ................ 381
Chapter 30—Commonly Used Surgical Procedures for
Women with Cancer.............................................. 385
Section 30.1—Hysterectomy............................ 386
Section 30.2—Mastectomy............................... 393
Section 30.3—Oophorectomy........................... 407
Section 30.4—Laparoscopy.............................. 410
Section 30.5—Cryosurgery .............................. 412
Chapter 31—Chemotherapy....................................................... 417
x
Chapter 32—Radiation Therapy ................................................ 423
Chapter 33—Bone Marrow and Peripheral Blood
Stem Cell Transplantation................................... 435
Chapter 34—Biological Therapies for Cancer ........................... 445
Chapter 35—Laser Treatment and Photodynamic
Therapy ................................................................. 453
Chapter 36—If You Are Considering Complementary
and Alternative Medicine Treatments
for Cancer.............................................................. 459
Chapter 37—Cancer Clinical Trials........................................... 469
Part VI: Coping with the Side Effects of Cancer and
Cancer Treatments
Chapter 38—Nausea and Vomiting ........................................... 485
Chapter 39—Gastrointestinal Effects of Cancer Treatment .... 491
Chapter 40—Controlling Cancer-Related Pain ......................... 505
Chapter 41—Lymphedema......................................................... 519
Chapter 42—The Effects of Cancer Treatments
on Blood Cells ....................................................... 529
Section 42.1—Anemia...................................... 530
Section 42.2—Neutropenia.............................. 532
Section 42.3—Thrombocytopenia.................... 537
Chapter 43—Fever, Sweats, and Hot Flashes ........................... 541
Chapter 44—Treatment-Related Neuropathy........................... 547
Chapter 45—Cancer Treatment and Physical Appearance...... 557
Section 45.1—Hair Loss (Alopecia)................. 558
Section 45.2—Nail and Skin Care................... 560
Chapter 46—Cognitive-Related Effects
of Cancer Treatment............................................. 563
Chapter 47—Fighting Cancer Fatigue....................................... 569
xi
Part VII: Women’s Issues in Cancer Survivorship
Chapter 48—Living with Cancer ............................................... 579
Section 48.1—Cancer Changes Everything.... 580
Section 48.2—Tips for Cancer Patients .......... 587
Chapter 49—Eating Well When You Have Cancer.................... 589
Chapter 50—Exercising During Cancer Treatment
and Beyond............................................................ 595
Chapter 51—Coping with the Emotions of Cancer ................... 601
Chapter 52—Talking to Your Children about Cancer............... 609
Chapter 53—Sexuality and Reproductive Issues
among Women with Cancer.................................. 615
Section 53.1—Renewing Intimacy and
Sexuality after Gynecologic
Cancer....................................... 616
Section 53.2—Cancer and Fertility
Preservation ............................. 621
Section 53.3—Pregnancy and Cancer ............. 624
Chapter 54—Taking Charge of Your Follow-Up Care............... 629
Part VIII: Additional Help and Information
Chapter 55—Glossary of Cancer Terms..................................... 635
Chapter 56—Resources for More Information
about Cancer in Women ....................................... 649
Chapter 57—How to Find a Cancer Support Group ................. 663
Index........................................................................................... 671
xiii
Preface
About This Book
According to the National Cancer Institute, cancer continues to take
a devastating toll. Among women in the United States, cancer is the
second-leading cause of death after heart disease. Medical researchers
fighting against cancer have made significant progress, however. In
recent years, cancer incidence rates have been stable, and—although
the annual rate of decline in cancer death rates among men have been
twice as large as the declines in women—mortality has decreased for
ten of the top 15 cancers in women. With improved cancer screening
programs and innovative treatments, women receiving a cancer diagnosis today have a better chance of overcoming their disease than
ever before.
Cancer Sourcebook for Women, Fourth Edition offers updated information about gynecologic cancers and other cancers of special
concern to women, including breast cancer, cancers of the female reproductive organs, and cancers responsible for the highest number of
deaths in women. It explains cancer risks—including lifestyle factors,
inherited genetic abnormalities, and hormonal medications—and
methods used to diagnose and treat cancer. Practical suggestions for
coping with the treatment side effects are provided, and a section on
cancer survivorship discusses methods for maintaining quality of life
during and after treatment. The book concludes with a glossary of
cancer-related terms, a directory of resources, and facts about locating support groups.